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Healthcare use and healthcare costs for patients with advanced cancer; the international ACTION cluster-randomised trial on advance care planning

Research output: Contribution to Journal/MagazineJournal articlepeer-review

  • Ida J Korfage
  • S. Polinder
  • Nancy Preston
  • Johannes J. M. van Delden
  • A Geraerds
  • Lesley Dunleavy
  • K. Faes
  • Guido; Miccinesi
  • Giulia Carreras
  • Caroline Arnfeldt
  • M. C. Kars
  • Giuseppe Lippi
  • Urska Lunder
  • Ceu Mateus
  • Kristian Pollock
  • Luc Deliens
  • M. Groenvold
  • Agnes van der Heide
  • Judith Rietjens
<mark>Journal publication date</mark>15/11/2022
<mark>Journal</mark>Palliative Medicine
Publication StatusAccepted/In press
<mark>Original language</mark>English


Background: Advance care planning supports patients to reflect on and discuss preferences for future treatment and care. Studies of the impact of advance care planning on healthcare use and healthcare costs are scarce.
Aim: To determine the impact on healthcare use and costs of an advance care planning intervention across six European countries.
Design: Cluster-randomised trial, registered as ISRCTN63110516, of advance care planning conversations supported by certified facilitators.
Setting/participants: Patients with advanced lung or colorectal cancer from 23 hospitals in Belgium, Denmark, Italy, the Netherlands, Slovenia and the UK. Data on healthcare use were collected from hospital medical files during 12 months after inclusion.
Results: Patients with a good performance status were underrepresented in the intervention group (preceived systemic cancer treatment; 79% versus 89%, respectively (pcountry, religion and WHO-status. No effect of the intervention on differences in costs between study groups was observed (p=0.3).
Conclusions: Lower care costs as observed in the intervention group were mainly related to patients’ characteristics. A definite impact of the intervention itself could not be established.