Heterobimetallic catalysis: Platinum-gold-catalyzed tandem cyclization/C−X coupling reaction of (hetero)arylallenes with nucleophiles

Chemistry

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Heterobimetallic catalysis: Platinum-gold-catalyzed tandem cyclization/C−X coupling reaction of (hetero)arylallenes with nucleophiles. / Alonso, José Miguel; Muñoz, Maria Paz.
In: Angewandte Chemie International Edition, Vol. 57, No. 17, 01.03.2018, p. 4742-4746.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Alonso, JM & Muñoz, MP 2018, 'Heterobimetallic catalysis: Platinum-gold-catalyzed tandem cyclization/C−X coupling reaction of (hetero)arylallenes with nucleophiles', Angewandte Chemie International Edition, vol. 57, no. 17, pp. 4742-4746. https://doi.org/10.1002/anie.201800670

APA

Alonso, J. M., & Muñoz, M. P. (2018). Heterobimetallic catalysis: Platinum-gold-catalyzed tandem cyclization/C−X coupling reaction of (hetero)arylallenes with nucleophiles. Angewandte Chemie International Edition, 57(17), 4742-4746. https://doi.org/10.1002/anie.201800670

Vancouver

Alonso JM, Muñoz MP. Heterobimetallic catalysis: Platinum-gold-catalyzed tandem cyclization/C−X coupling reaction of (hetero)arylallenes with nucleophiles. Angewandte Chemie International Edition. 2018 Mar 1;57(17):4742-4746. doi: 10.1002/anie.201800670

Author

Alonso, José Miguel ; Muñoz, Maria Paz. / Heterobimetallic catalysis: Platinum-gold-catalyzed tandem cyclization/C−X coupling reaction of (hetero)arylallenes with nucleophiles. In: Angewandte Chemie International Edition. 2018 ; Vol. 57, No. 17. pp. 4742-4746.

Bibtex

@article{f443cc7b2d354aa484ea5aa46f9cbb62,

title = "Heterobimetallic catalysis: Platinum-gold-catalyzed tandem cyclization/C−X coupling reaction of (hetero)arylallenes with nucleophiles",

abstract = "Heterobimetallic catalysis offers new opportunities for reactivity and selectivity but still presents challenges, and only a few metal combinations have been explored so far. Reported here is a Pt‐Au heterobimetallic catalyst system for the synthesis of a family of multi‐heteroaromatic structures through tandem cyclization/C−X coupling reaction. Au‐catalyzed 6‐endo‐cyclization takes place as the first fast step. Pt‐Au clusters are proposed to be responsible for the increased reactivity in the second step, that is, the intermolecular nucleophilic addition which occurs through an outer‐sphere mechanism by hybrid homogeneous‐heterogeneous catalysis.",

keywords = "heterobimetallic catalysis, hybrid-homogeneous heterogeneous catalysis, platinum, gold, allenes",

author = "Alonso, {Jos{\'e} Miguel} and Mu{\~n}oz, {Maria Paz}",

year = "2018",

month = mar,

day = "1",

doi = "10.1002/anie.201800670",

language = "English",

volume = "57",

pages = "4742--4746",

journal = "Angewandte Chemie International Edition",

issn = "1433-7851",

publisher = "Wiley-VCH Verlag",

number = "17",

}

RIS

TY - JOUR

T1 - Heterobimetallic catalysis: Platinum-gold-catalyzed tandem cyclization/C−X coupling reaction of (hetero)arylallenes with nucleophiles

AU - Alonso, José Miguel

AU - Muñoz, Maria Paz

PY - 2018/3/1

Y1 - 2018/3/1

N2 - Heterobimetallic catalysis offers new opportunities for reactivity and selectivity but still presents challenges, and only a few metal combinations have been explored so far. Reported here is a Pt‐Au heterobimetallic catalyst system for the synthesis of a family of multi‐heteroaromatic structures through tandem cyclization/C−X coupling reaction. Au‐catalyzed 6‐endo‐cyclization takes place as the first fast step. Pt‐Au clusters are proposed to be responsible for the increased reactivity in the second step, that is, the intermolecular nucleophilic addition which occurs through an outer‐sphere mechanism by hybrid homogeneous‐heterogeneous catalysis.

AB - Heterobimetallic catalysis offers new opportunities for reactivity and selectivity but still presents challenges, and only a few metal combinations have been explored so far. Reported here is a Pt‐Au heterobimetallic catalyst system for the synthesis of a family of multi‐heteroaromatic structures through tandem cyclization/C−X coupling reaction. Au‐catalyzed 6‐endo‐cyclization takes place as the first fast step. Pt‐Au clusters are proposed to be responsible for the increased reactivity in the second step, that is, the intermolecular nucleophilic addition which occurs through an outer‐sphere mechanism by hybrid homogeneous‐heterogeneous catalysis.

KW - heterobimetallic catalysis

KW - hybrid-homogeneous heterogeneous catalysis

KW - platinum

KW - gold

KW - allenes

U2 - 10.1002/anie.201800670

DO - 10.1002/anie.201800670

M3 - Journal article

VL - 57

SP - 4742

EP - 4746

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

SN - 1433-7851

IS - 17

ER -

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