Research output: Contribution to Journal/Magazine › Journal article › peer-review
High-affinity ultivalent DNA binding by using low-molecular-weight dendrons. / Kostiainen, Mauri A.; Hardy, John G.; Smith, David K.
In: Angewandte Chemie International Edition, Vol. 44, No. 17, 22.04.2005, p. 2556-2559.Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - High-affinity ultivalent DNA binding by using low-molecular-weight dendrons
AU - Kostiainen, Mauri A.
AU - Hardy, John G.
AU - Smith, David K.
PY - 2005/4/22
Y1 - 2005/4/22
N2 - Nine spermines are better than one: Compound G2 exhibits high-affinity, salt-independent DNA binding as a consequence of the spermine array on its surface. Comparison with smaller dendrons and model compounds indicates a clear multivalency effect on binding.
AB - Nine spermines are better than one: Compound G2 exhibits high-affinity, salt-independent DNA binding as a consequence of the spermine array on its surface. Comparison with smaller dendrons and model compounds indicates a clear multivalency effect on binding.
KW - dendrimers
KW - DNA
KW - multivalency
KW - nanochemistry
KW - self-assembly
KW - VITRO GENE TRANSFECTION
KW - IN-VITRO
KW - CASCADE POLYMERS
KW - POLYAMIDOAMINE DENDRIMERS
KW - DENDRITIC MACROMOLECULES
KW - SUPRAMOLECULAR CHEMISTRY
KW - CATIONIC LIPIDS
KW - PLASMID DNA
KW - DELIVERY
KW - SPERMINE
U2 - 10.1002/anie.200500066
DO - 10.1002/anie.200500066
M3 - Journal article
VL - 44
SP - 2556
EP - 2559
JO - Angewandte Chemie International Edition
JF - Angewandte Chemie International Edition
SN - 1433-7851
IS - 17
ER -