Final published version
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Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - ICTV Virus Taxonomy Profile
T2 - Herpesviridae 2021
AU - Gatherer, Derek
AU - Depledge, Daniel P
AU - Hartley, Carol A
AU - Szpara, Moriah L
AU - Vaz, Paola K
AU - Benkő, Mária
AU - Brandt, Curtis R
AU - Bryant, Neil A
AU - Dastjerdi, Akbar
AU - Doszpoly, Andor
AU - Gompels, Ursula A
AU - Inoue, Naoki
AU - Jarosinski, Keith W
AU - Kaul, Rajeev
AU - Lacoste, Vincent
AU - Norberg, Peter
AU - Origgi, Francesco C
AU - Orton, Richard J
AU - Pellett, Philip E
AU - Schmid, D Scott
AU - Spatz, Stephen J
AU - Stewart, James P
AU - Trimpert, Jakob
AU - Waltzek, Thomas B
AU - Davison, Andrew J
PY - 2021/10/27
Y1 - 2021/10/27
N2 - Members of the family Herpesviridae have enveloped, spherical virions with characteristic complex structures consisting of symmetrical and non-symmetrical components. The linear, double-stranded DNA genomes of 125-241 kbp contain 70-170 genes, of which 43 have been inherited from an ancestral herpesvirus. In general, herpesviruses have coevolved with and are highly adapted to their hosts, which comprise many mammalian, avian and reptilian species. Following primary infection, they are able to establish lifelong latent infection, during which there is limited viral gene expression. Severe disease is usually observed only in the foetus, the very young, the immunocompromised or following infection of an alternative host. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Herpesviridae, which is available at ictv.global/report/herpesviridae.
AB - Members of the family Herpesviridae have enveloped, spherical virions with characteristic complex structures consisting of symmetrical and non-symmetrical components. The linear, double-stranded DNA genomes of 125-241 kbp contain 70-170 genes, of which 43 have been inherited from an ancestral herpesvirus. In general, herpesviruses have coevolved with and are highly adapted to their hosts, which comprise many mammalian, avian and reptilian species. Following primary infection, they are able to establish lifelong latent infection, during which there is limited viral gene expression. Severe disease is usually observed only in the foetus, the very young, the immunocompromised or following infection of an alternative host. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Herpesviridae, which is available at ictv.global/report/herpesviridae.
KW - Herpesvirales
KW - Herpesviridae
KW - Taxonomy
KW - virology
KW - herpes
KW - herpesvirus
KW - virus
KW - Evolution
U2 - 10.1099/jgv.0.001673
DO - 10.1099/jgv.0.001673
M3 - Journal article
C2 - 34704922
VL - 102
JO - Journal of General Virology
JF - Journal of General Virology
SN - 0022-1317
IS - 10
ER -