Rights statement: This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Final published version, 2.46 MB, PDF document
Available under license: CC BY
Research output: Contribution to Journal/Magazine › Literature review › peer-review
Research output: Contribution to Journal/Magazine › Literature review › peer-review
}
TY - JOUR
T1 - Illuminating disease and enlightening biomedicine
T2 - Raman spectroscopy as a diagnostic tool
AU - Ellis, David I.
AU - Cowcher, David P.
AU - Ashton, Lorna
AU - O'Hagan, Steve
AU - Goodacre, Royston
N1 - This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
PY - 2013
Y1 - 2013
N2 - The discovery of the Raman effect in 1928 not only aided fundamental understanding about the quantum nature of light and matter but also opened up a completely novel area of optics and spectroscopic research that is accelerating at a greater rate during the last decade than at any time since its inception. This introductory overview focuses on some of the most recent developments within this exciting field and how this has enabled and enhanced disease diagnosis and biomedical applications. We highlight a small number of stimulating high-impact studies in imaging, endoscopy, stem cell research, and other recent developments such as spatially offset Raman scattering amongst others. We hope this stimulates further interest in this already exciting field, by 'illuminating' some of the current research being undertaken by the latest in a very long line of dedicated experimentalists interested in the properties and potential beneficial applications of light.
AB - The discovery of the Raman effect in 1928 not only aided fundamental understanding about the quantum nature of light and matter but also opened up a completely novel area of optics and spectroscopic research that is accelerating at a greater rate during the last decade than at any time since its inception. This introductory overview focuses on some of the most recent developments within this exciting field and how this has enabled and enhanced disease diagnosis and biomedical applications. We highlight a small number of stimulating high-impact studies in imaging, endoscopy, stem cell research, and other recent developments such as spatially offset Raman scattering amongst others. We hope this stimulates further interest in this already exciting field, by 'illuminating' some of the current research being undertaken by the latest in a very long line of dedicated experimentalists interested in the properties and potential beneficial applications of light.
KW - EMBRYONIC STEM-CELLS
KW - IN-VIVO
KW - SCATTERING MICROSCOPY
KW - BREAST-CANCER
KW - PROSTATE-CANCER
KW - CARS MICROSCOPY
KW - NONINVASIVE DETECTION
KW - RAPID IDENTIFICATION
KW - BARRETTS-ESOPHAGUS
KW - CHEMICAL-ANALYSIS
U2 - 10.1039/c3an00698k
DO - 10.1039/c3an00698k
M3 - Literature review
VL - 138
SP - 3871
EP - 3884
JO - Analyst
JF - Analyst
SN - 0003-2654
IS - 14
ER -