Embedded computing systems have become a pervasive aspect in virtually all application domains, such as industrial, mobile communication, transportation and medical. Due to increasing computational capabilities of microcomputers and their decreasing cost, new functionality has been enabled (e.g., driver assistance systems) and cost savings have become possible, e.g., by the replacement of mechanical components by embedded computers. Conventionally, each application domain tends to develop customized solutions, often re-inventing concepts that are already applied in other domains. It is therefore expedient to invest into a generic embedded system architecture that supports the development of dependable embedded applications in many different application domains, using the same hardware devices and software modules. INDEXYS targets to pave the way from the European Commission Framework 7 GENESYS Project reference computing architecture approach towards pilot applications in the automotive-, railway- and aerospace industrial domains. INDEXYS will follow-up GENESYS project results and will implement selected industrial-grade services of GENESYS architectural concepts. The results of laying together GENESYS, INDEXYS and the new ARTEMIS project ACROSS, which will develop multi processor systems on a chip (MPSoC) using GENESYS reference architecture and services, will provide integral cross-domain architecture and platform, design- and verification- tools, middleware and flexible FPGA- or chip- based devices lowering OEM cost of development and production at faster time-to market.n of COOPERS. © 2010 Springer-Verlag Berlin Heidelberg.