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Instructive conductive 3D silk foam-based bone tissue scaffolds enable electrical stimulation of stem cells for enhanced osteogenic differentiation

Research output: Contribution to Journal/MagazineJournal articlepeer-review

  • John G. Hardy
  • Sydney A. Geissler
  • David Aguilar Jr.
  • Maria K. Villancio-Wolter
  • David J. Mouser
  • Rushi C. Sukhavasi
  • R. Chase Cornelison
  • Lee W. Tien
  • R. Carmen Preda
  • Rebecca S. Hayden
  • Jacqueline K. Chow
  • Lindsey Nguy
  • David L. Kaplan
  • Christine E. Schmidt
<mark>Journal publication date</mark>11/2015
<mark>Journal</mark>Macromolecular Bioscience
Issue number11
Number of pages7
Pages (from-to)1490-1496
Publication StatusPublished
Early online date1/06/15
<mark>Original language</mark>English


Stimuli-responsive materials enabling the behaviour of the cells that reside within them to be controlled are vital for the development of instructive tissue scaffolds for tissue engineering. Herein we describe the preparation of conductive silk foam-based bone tissue scaffolds that enable the electrical stimulation of human mesenchymal stem cells to enhance their differentiation towards osteogenic outcomes.