Rights statement: This is the peer reviewed version of the following article: Allen, R. J., Atkinson, A. L., Vargha-Khadem, F., & Baddeley, A. D. (2022). Intact high-resolution working memory binding in a patient with developmental amnesia and selective hippocampal damage. Hippocampus, 32( 8), 597– 609. doi: 10.1002/hipo.23452 which has been published in final form at https://onlinelibrary.wiley.com/action/showCitFormats?doi=10.1002%2Fhipo.23452 This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.
Accepted author manuscript, 1.39 MB, PDF document
Available under license: CC BY-NC: Creative Commons Attribution-NonCommercial 4.0 International License
Final published version
Licence: CC BY: Creative Commons Attribution 4.0 International License
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Intact high-resolution working memory binding in a patient with developmental amnesia and selective hippocampal damage
AU - Allen, Richard J
AU - Atkinson, Amy
AU - Vargha-Khadem, Faraneh
AU - Baddeley, Alan D
N1 - This is the peer reviewed version of the following article: Allen, R. J., Atkinson, A. L., Vargha-Khadem, F., & Baddeley, A. D. (2022). Intact high-resolution working memory binding in a patient with developmental amnesia and selective hippocampal damage. Hippocampus, 32( 8), 597– 609. doi: 10.1002/hipo.23452 which has been published in final form at https://onlinelibrary.wiley.com/action/showCitFormats?doi=10.1002%2Fhipo.23452 This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.
PY - 2022/8/31
Y1 - 2022/8/31
N2 - Debate continues regarding the possible role of the hippocampus across short-term and working memory tasks. The current study examined the possibility of a hippocampal contribution to precise, high-resolution cognition and conjunctive memory. We administered visual working memory tasks featuring a continuous response component to a well-established developmental amnesic patientwith relatively selective bilateral hippocampal damage (Jon), and healthy controls. The patient was able to produce highly accurate response judgments regarding conjunctions of color and orientation or color and location, using simultaneous or sequential presentation of stimuli, with no evidence of any impairment in working memory binding, categorical accuracy or continuous precision. These findings indicate that hippocampal damage does not necessarily lead to deficits in high resolution cognitive performance, even when the damage is severe and bilateral.
AB - Debate continues regarding the possible role of the hippocampus across short-term and working memory tasks. The current study examined the possibility of a hippocampal contribution to precise, high-resolution cognition and conjunctive memory. We administered visual working memory tasks featuring a continuous response component to a well-established developmental amnesic patientwith relatively selective bilateral hippocampal damage (Jon), and healthy controls. The patient was able to produce highly accurate response judgments regarding conjunctions of color and orientation or color and location, using simultaneous or sequential presentation of stimuli, with no evidence of any impairment in working memory binding, categorical accuracy or continuous precision. These findings indicate that hippocampal damage does not necessarily lead to deficits in high resolution cognitive performance, even when the damage is severe and bilateral.
KW - developmental amnesia
KW - hippocampus
KW - memory precision
KW - short-term memory
KW - visual working memory
U2 - 10.1002/hipo.23452
DO - 10.1002/hipo.23452
M3 - Journal article
VL - 32
SP - 597
EP - 609
JO - Hippocampus
JF - Hippocampus
SN - 1050-9631
IS - 8
ER -