Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans

Data Science Institute

Keywords

Africa, African Continental Ancestry Group, Caribbean Region, Chromosome Mapping, Chromosomes, Human, Pair 17, Cohort Studies, Genetic Linkage, Humans, Hypertension

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans. / Knight, Jo; Gardner, G. T.; Clark, A. J. et al.
In: Journal of Human Hypertension, Vol. 14, No. 6, 06.2000, p. 385-387.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Author

Knight, Jo ; Gardner, G. T. ; Clark, A. J. et al. / Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans. In: Journal of Human Hypertension. 2000 ; Vol. 14, No. 6. pp. 385-387.

Bibtex

@article{65d7ac9215a842a5bbcc833cb5ba1afb,

title = "Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans",

abstract = "Essential hypertension is a major risk factor for cardiovascular disease in humans, and originates from both genetic and environmental factors. Data from animal and more recently human studies have indicated the presence of a gene influencing blood pressure on human chromosome 17. This study tested for linkage of markers located on chromosome 17q to essential hypertension in African Caribbean hypertensive families. No support of linkage was found between the markers studied and hypertension, however only genes of a lamda sib value of less than 1.8 could be excluded.",

keywords = "Africa, African Continental Ancestry Group, Caribbean Region, Chromosome Mapping, Chromosomes, Human, Pair 17, Cohort Studies, Genetic Linkage, Humans, Hypertension",

author = "Jo Knight and Gardner, {G. T.} and Clark, {A. J.} and Caulfield, {M. J.}",

year = "2000",

month = jun,

language = "English",

volume = "14",

pages = "385--387",

journal = "Journal of Human Hypertension",

issn = "0950-9240",

publisher = "Nature Publishing Group",

number = "6",

}

RIS

TY - JOUR

T1 - Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans

AU - Knight, Jo

AU - Gardner, G. T.

AU - Clark, A. J.

AU - Caulfield, M. J.

PY - 2000/6

Y1 - 2000/6

N2 - Essential hypertension is a major risk factor for cardiovascular disease in humans, and originates from both genetic and environmental factors. Data from animal and more recently human studies have indicated the presence of a gene influencing blood pressure on human chromosome 17. This study tested for linkage of markers located on chromosome 17q to essential hypertension in African Caribbean hypertensive families. No support of linkage was found between the markers studied and hypertension, however only genes of a lamda sib value of less than 1.8 could be excluded.

AB - Essential hypertension is a major risk factor for cardiovascular disease in humans, and originates from both genetic and environmental factors. Data from animal and more recently human studies have indicated the presence of a gene influencing blood pressure on human chromosome 17. This study tested for linkage of markers located on chromosome 17q to essential hypertension in African Caribbean hypertensive families. No support of linkage was found between the markers studied and hypertension, however only genes of a lamda sib value of less than 1.8 could be excluded.

KW - Africa

KW - African Continental Ancestry Group

KW - Caribbean Region

KW - Chromosome Mapping

KW - Chromosomes, Human, Pair 17

KW - Cohort Studies

KW - Genetic Linkage

KW - Humans

KW - Hypertension

M3 - Journal article

C2 - 10878700

VL - 14

SP - 385

EP - 387

JO - Journal of Human Hypertension

JF - Journal of Human Hypertension

SN - 0950-9240

IS - 6

ER -

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