Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Lateralisation of auditory processing in Down syndrome: A study of T-complex peaks Ta and Tb. / Groen, Margriet Anna; Alku, Paavo; Bishop, Dorothy Vera Margaret.
In: Biological Psychology, Vol. 79, No. 2, 2008, p. 148-157.Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Lateralisation of auditory processing in Down syndrome: A study of T-complex peaks Ta and Tb
AU - Groen, Margriet Anna
AU - Alku, Paavo
AU - Bishop, Dorothy Vera Margaret
PY - 2008
Y1 - 2008
N2 - It has long been argued that abnormal cerebral lateralisation might underlie the language problems that characterise Down syndrome, but to date only behavioural evidence has been provided. We used the auditory event-related potentials Ta and Tb of the T-complex to investigate lateralised processing of speech (vowels) and non-speech (simple and complex tones) sounds in children with Down syndrome and age-matched typically developing children. We also explored associations with speech and language abilities. Although changes in the Ta and Tb in response to increases in stimulus complexity and ‘speechness’ were similar across group, the Tb peak was delayed in children with Down syndrome across conditions. In addition, marked differences in the patterns of lateralisation of Ta latency and Tb amplitude were observed in children with Down syndrome, in response to both speech and non-speech sounds. No associations were found between Ta and Tb characteristics and speech and language abilities in children with DS.
AB - It has long been argued that abnormal cerebral lateralisation might underlie the language problems that characterise Down syndrome, but to date only behavioural evidence has been provided. We used the auditory event-related potentials Ta and Tb of the T-complex to investigate lateralised processing of speech (vowels) and non-speech (simple and complex tones) sounds in children with Down syndrome and age-matched typically developing children. We also explored associations with speech and language abilities. Although changes in the Ta and Tb in response to increases in stimulus complexity and ‘speechness’ were similar across group, the Tb peak was delayed in children with Down syndrome across conditions. In addition, marked differences in the patterns of lateralisation of Ta latency and Tb amplitude were observed in children with Down syndrome, in response to both speech and non-speech sounds. No associations were found between Ta and Tb characteristics and speech and language abilities in children with DS.
KW - Down syndrome
KW - Event-related potential
KW - Auditory
KW - T-complex
KW - Speech sounds
KW - Tones
KW - Lateralisation
U2 - 10.1016/j.biopsycho.2008.04.003
DO - 10.1016/j.biopsycho.2008.04.003
M3 - Journal article
VL - 79
SP - 148
EP - 157
JO - Biological Psychology
JF - Biological Psychology
SN - 0301-0511
IS - 2
ER -