Final published version, 0.98 MB, PDF document
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Research output: Contribution to conference - Without ISBN/ISSN › Poster › peer-review
Research output: Contribution to conference - Without ISBN/ISSN › Poster › peer-review
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TY - CONF
T1 - Light-responsive polymer-based drug delivery systems
AU - Oikonomou, Vasileios
AU - Ashton, Mark
AU - Firlak, Melike
AU - Hardy, John
PY - 2018/5/28
Y1 - 2018/5/28
N2 - Light-responsive polymers have a variety of potential biomedical applications. Here we describe the development of light-responsive polymer-based drug delivery systems in which a photo-responsive unit is incorporated in the polymers facilitating structural changes in the polymers upon exposure to light of various wavelengths. The photoactive unit can either be incorporated in the backbone or pendant on the backbone, and the chemistry of the photoactive unit determines if the polymers change conformation/shape, degrade, etc. (and therefore the mechanism of drug delivery), and the wavelength of light to which the polymers respond. We report the synthesis and characterization of light-responsive polymers and their processing into various materials morphologies that enable the delivery of drugs with wide ranging molecular weights in vitro.
AB - Light-responsive polymers have a variety of potential biomedical applications. Here we describe the development of light-responsive polymer-based drug delivery systems in which a photo-responsive unit is incorporated in the polymers facilitating structural changes in the polymers upon exposure to light of various wavelengths. The photoactive unit can either be incorporated in the backbone or pendant on the backbone, and the chemistry of the photoactive unit determines if the polymers change conformation/shape, degrade, etc. (and therefore the mechanism of drug delivery), and the wavelength of light to which the polymers respond. We report the synthesis and characterization of light-responsive polymers and their processing into various materials morphologies that enable the delivery of drugs with wide ranging molecular weights in vitro.
M3 - Poster
T2 - Bordeaux Polymer Conference
Y2 - 28 May 2018 through 31 May 2018
ER -