Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Low dose, early mucosal exposure will minimize the risk of microbial disease
AU - Morris, James A
AU - Harrison, Linda M
AU - Lauder, Robert M
AU - Telford, David R
AU - Neary, Richard
N1 - Copyright © 2012 Elsevier Ltd. All rights reserved.
PY - 2012/11
Y1 - 2012/11
N2 - In the 21st century we will rediscover the germ theory of disease: germs not only cause infection as described in standard textbooks but also have a pathogenic role in autoimmunity, atherosclerosis, cancer and even acute psychiatric conditions. In order to reduce morbidity and mortality caused by common organisms we should ensure that exposure is early, often, by the mucosal route and in low dose. Micro-organisms should be delivered daily throughout life by respiratory mucosal spray or enteric coated pill, in precise dose and in a predetermined schedule.
AB - In the 21st century we will rediscover the germ theory of disease: germs not only cause infection as described in standard textbooks but also have a pathogenic role in autoimmunity, atherosclerosis, cancer and even acute psychiatric conditions. In order to reduce morbidity and mortality caused by common organisms we should ensure that exposure is early, often, by the mucosal route and in low dose. Micro-organisms should be delivered daily throughout life by respiratory mucosal spray or enteric coated pill, in precise dose and in a predetermined schedule.
U2 - 10.1016/j.mehy.2012.07.039
DO - 10.1016/j.mehy.2012.07.039
M3 - Journal article
C2 - 22959998
VL - 79
SP - 630
EP - 634
JO - Medical Hypotheses
JF - Medical Hypotheses
IS - 5
ER -