TY - JOUR

T1 - Low-Sound-Level Auditory Processing in Noise-Exposed Adults

AU - Perugia, Emanuele

AU - Plack, Christopher

AU - Stone, Michael

N1 - This is the author’s version of a work that was accepted for publication in Hearing Research. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Hearing Research, 409, 2021 DOI: 10.1016/j.heares.2021.108309

PY - 2021/9/30

Y1 - 2021/9/30

N2 - Early signs of noise-induced hearing damage are difficult to identify, as they are often confounded by factors such as age, audiometric thresholds, or even music experience. Much previous research has focused on deficits observed at high intensity levels. In contrast, the present study was designed to test the hypothesis that noise exposure causes a degradation in low-sound-level auditory processing in humans, as a consequence of dysfunction of the inner hair cell pathway. Frequency difference limens (FDLs) and amplitude modulation depth discrimination (MDD) were measured for five center frequencies (0.75, 1, 3, 4 and 6 kHz) at 15 and 25 dB sensation level (SL), as a function of noise exposure, age, audiometric hearing loss, and music experience. Forty participants, aged 33-75 years, with normal hearing up to 1 kHz and mild-to-moderate hearing loss above 2 kHz, were tested. Participants had varying degrees of self-reported noise exposure, and varied in music experience. FDL worsened as a function of age. Participants with music experience outperformed the non-experienced in both the FDL and MDD tasks. MDD thresholds were significantly better for high-noise-exposed, than for low-noise-exposed, participants at 25 dB SL, particularly at 6 kHz. No effects of age or hearing loss were observed in the MDD. It is possible that the association between MDD thresholds and noise exposure was not causal, but instead was mediated by other factors that were not measured in the study. The association is consistent, qualitatively, with a hypothesized loss of compression due to outer hair cell dysfunction.

AB - Early signs of noise-induced hearing damage are difficult to identify, as they are often confounded by factors such as age, audiometric thresholds, or even music experience. Much previous research has focused on deficits observed at high intensity levels. In contrast, the present study was designed to test the hypothesis that noise exposure causes a degradation in low-sound-level auditory processing in humans, as a consequence of dysfunction of the inner hair cell pathway. Frequency difference limens (FDLs) and amplitude modulation depth discrimination (MDD) were measured for five center frequencies (0.75, 1, 3, 4 and 6 kHz) at 15 and 25 dB sensation level (SL), as a function of noise exposure, age, audiometric hearing loss, and music experience. Forty participants, aged 33-75 years, with normal hearing up to 1 kHz and mild-to-moderate hearing loss above 2 kHz, were tested. Participants had varying degrees of self-reported noise exposure, and varied in music experience. FDL worsened as a function of age. Participants with music experience outperformed the non-experienced in both the FDL and MDD tasks. MDD thresholds were significantly better for high-noise-exposed, than for low-noise-exposed, participants at 25 dB SL, particularly at 6 kHz. No effects of age or hearing loss were observed in the MDD. It is possible that the association between MDD thresholds and noise exposure was not causal, but instead was mediated by other factors that were not measured in the study. The association is consistent, qualitatively, with a hypothesized loss of compression due to outer hair cell dysfunction.

KW - Sub-clinical hearing damage

KW - Noise exposure

KW - Noise-induced hearing loss

KW - Frequency difference limens

KW - Amplitude modulation depth discrimination

U2 - 10.1016/j.heares.2021.108309

DO - 10.1016/j.heares.2021.108309

M3 - Journal article

VL - 409

JO - Hearing Research

JF - Hearing Research

SN - 0378-5955

M1 - 108309

ER -