Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Low-Temperature Synthesis and Surface Modification of High Surface Area Calcium Hydroxyapatite Nanorods Incorporating Organofunctionalized Surfaces
AU - Anwar, A.
AU - Rehman, I.U.
AU - Darr, J.A.
PY - 2016/12/29
Y1 - 2016/12/29
N2 - A new low-temperature continuous approach for the surface modification of hydroxyapatite (HA) is described. In this method, the HA particle surfaces were modified using methacrylic acid, vinylphosphonic acid, adipic acid, citric acid, or polyvinyalcohol, respectively, using a continuous plastic flow synthesis (CPFS) system at a reaction temperature of 70 °C for 5 min. The materials were investigated using a range of analytical techniques, including TEM (transmission electron microscopy), zeta potential, XRD (X-ray diffraction), BET (Brunauer-Emmett-Teller) surface area analysis, FTIR (Fourier transform infrared) spectroscopy, and XPS (X-ray photoelectron spectroscopy). The presence of organic agents in the reagents, resulted in a significant reduction in particle size of the nano-HA rods; TEM studies confirmed the formation of highly dispersed nanorods of HA with average lengths and diameters in the ranges 20-60 nm and 4-10 nm, respectively. XPS analyses suggested that the Ca:P molar ratio decreased from 1.67 to ca. 1.34 by the addition of organic surface agents. The zeta potential measurements revealed that the colloidal stability of surface-modified HA generally increased (under certain conditions) compared to ungrafted HA. The small size and presence of functional groups make these materials potentially suitable for dental restoration fillers and composite bone regeneration applications. © 2016 American Chemical Society.
AB - A new low-temperature continuous approach for the surface modification of hydroxyapatite (HA) is described. In this method, the HA particle surfaces were modified using methacrylic acid, vinylphosphonic acid, adipic acid, citric acid, or polyvinyalcohol, respectively, using a continuous plastic flow synthesis (CPFS) system at a reaction temperature of 70 °C for 5 min. The materials were investigated using a range of analytical techniques, including TEM (transmission electron microscopy), zeta potential, XRD (X-ray diffraction), BET (Brunauer-Emmett-Teller) surface area analysis, FTIR (Fourier transform infrared) spectroscopy, and XPS (X-ray photoelectron spectroscopy). The presence of organic agents in the reagents, resulted in a significant reduction in particle size of the nano-HA rods; TEM studies confirmed the formation of highly dispersed nanorods of HA with average lengths and diameters in the ranges 20-60 nm and 4-10 nm, respectively. XPS analyses suggested that the Ca:P molar ratio decreased from 1.67 to ca. 1.34 by the addition of organic surface agents. The zeta potential measurements revealed that the colloidal stability of surface-modified HA generally increased (under certain conditions) compared to ungrafted HA. The small size and presence of functional groups make these materials potentially suitable for dental restoration fillers and composite bone regeneration applications. © 2016 American Chemical Society.
KW - Calcium
KW - Filling
KW - Fourier transform infrared spectroscopy
KW - High resolution transmission electron microscopy
KW - Hydroxyapatite
KW - Low temperature effects
KW - Nanorods
KW - Particle size
KW - Surface treatment
KW - Temperature
KW - Transmission electron microscopy
KW - X ray diffraction
KW - Zeta potential
KW - Brunauer emmett tellers
KW - Calcium hydroxyapatite
KW - Fourier transform infra reds
KW - Low temperature synthesis
KW - Surface area analysis
KW - TEM (transmission electron microscopy)
KW - Xrd (x ray diffraction)
KW - Zeta potential measurements
KW - X ray photoelectron spectroscopy
U2 - 10.1021/acs.jpcc.6b05878
DO - 10.1021/acs.jpcc.6b05878
M3 - Journal article
VL - 120
SP - 29069
EP - 29076
JO - Journal of Physical Chemistry C
JF - Journal of Physical Chemistry C
SN - 1932-7447
IS - 51
ER -