Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Mathematical optimization in intensity modulated radiation therapy
AU - Ehrgott, Matthias
AU - Güler, Çiğdem
AU - Hamacher, Horst W.
AU - Shao, Lizhen
PY - 2008/9/1
Y1 - 2008/9/1
N2 - The design of an intensity modulated radiotherapy treatment includes the selection of beam angles (geometry problem), the computation of an intensity map for each selected beam angle (intensity problem), and finding a sequence of configurations of a multileaf collimator to deliver the treatment (realization problem). Until the end of the last century research on radiotherapy treatment design has been published almost exclusively in the medical physics literature. However, since then, the attention of researchers in mathematical optimization has been drawn to the area and important progress has been made. In this paper we survey the use of optimization models, methods, and theories in intensity modulated radiotherapy treatment design.
AB - The design of an intensity modulated radiotherapy treatment includes the selection of beam angles (geometry problem), the computation of an intensity map for each selected beam angle (intensity problem), and finding a sequence of configurations of a multileaf collimator to deliver the treatment (realization problem). Until the end of the last century research on radiotherapy treatment design has been published almost exclusively in the medical physics literature. However, since then, the attention of researchers in mathematical optimization has been drawn to the area and important progress has been made. In this paper we survey the use of optimization models, methods, and theories in intensity modulated radiotherapy treatment design.
KW - Intensity modulated radiation therapy
KW - Optimization
KW - Mathematical models
KW - Medical physics
U2 - 10.1007/s10288-008-0083-7
DO - 10.1007/s10288-008-0083-7
M3 - Journal article
VL - 6
SP - 199
EP - 262
JO - 4OR: A Quarterly Journal of Operations Research
JF - 4OR: A Quarterly Journal of Operations Research
SN - 1619-4500
IS - 3
ER -