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  • Hardy_Schmidt_Suggs_Murphy_JBMRB_sub

    Rights statement: This is the peer reviewed version of the following article: Harrison R, Criss ZK, Feller L, Modi SP, Hardy JG, Schmidt CE, Suggs LJ, Murphy MB. 2016. Mechanical properties of α-tricalcium phosphate-based bone cements incorporating regenerative biomaterials for filling bone defects exposed to low mechanical loads. J Biomed Mater Res Part B 2016:104B:149–157 which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33362/abstract This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.

    Accepted author manuscript, 158 KB, PDF document

  • Hardy_Schmidt_Suggs_Murphy_JBMRB_SI_sub

    Rights statement: This is the peer reviewed version of the following article: Harrison R, Criss ZK, Feller L, Modi SP, Hardy JG, Schmidt CE, Suggs LJ, Murphy MB. 2016. Mechanical properties of α-tricalcium phosphate-based bone cements incorporating regenerative biomaterials for filling bone defects exposed to low mechanical loads. J Biomed Mater Res Part B 2016:104B:149–157 which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33362/abstract This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.

    Accepted author manuscript, 440 KB, PDF document

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Mechanical properties of α-tricalcium phosphate-based bone cements incorporating regenerative biomaterials for filling bone defects exposed to low mechanical loads

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Published
  • Reed Harrison
  • Zachary K. Criss
  • Lacie Feller
  • Shan P. Modi
  • John G. Hardy
  • Christine E. Schmidt
  • Laura J. Suggs
  • Matthew B. Murphy
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<mark>Journal publication date</mark>01/2016
<mark>Journal</mark>Journal of Biomedical Materials Research Part B: Applied Biomaterials
Issue number1
Volume104
Number of pages9
Pages (from-to)149-157
Publication StatusPublished
Early online date10/02/15
<mark>Original language</mark>English

Abstract

Calcium phosphate-based cements with enhanced regenerative potential are promising biomaterials for the healing of bone defects. With a view to the use of such cements for low load bearing applications such as sinus augmentation or filling extraction sites, we have prepared α-tricalcium phosphate (α-TCP)-based bone cements including materials that we would expect to improve their regenerative potential, and describe the mechanical properities of the resulting formulations herein. Formulations incorporated α-TCP, hydroxyapatite, biopolymer-thickened wetting agents, sutures, and platelet poor plasma. The mechanical properties of the composites were composition dependent, and optimized formulations had clinically relevant mechanical properties. Such calcium phosphate-based cements have potential as replacements for cements such as those based on polymethylmethacrylate (PMMA).

Bibliographic note

This is the peer reviewed version of the following article: Chrisman, J. J., Fang, H., Kotlar, J. and De Massis, A. (2014), A Note on Family Influence and the Adoption of Discontinuous Technologies in Family Firms. Journal of Product Innovation Management. doi: 10.1111/jpim.12206 which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1111/jpim.12206/abstract This article may be used for non-commercial purposes in accordance With Wiley Terms and Conditions for self-archiving.