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Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Mediation analysis of recovery-focused therapy for recent-onset bipolar disorder
AU - Jones, Steven
AU - Knowles, Dawn
AU - Howarth, Elizabeth
AU - Lobban, Fiona
AU - Emsley, Richard
PY - 2021/7/31
Y1 - 2021/7/31
N2 - BackgroundRecovery focused therapy has been shown to improve recovery outcomes in individuals with recent onset bipolar disorder. However the process by which this is achieved is unclear. This paper therefore examines potential mediators of this effect using data from a randomised controlled trial comparing recovery focused therapy with treatment as usual (ISRCTN43062149).MethodsA single-blind randomised controlled trial compared treatment as usual (TAU) with recovery-focused therapy (RfT) plus TAU (n = 67) in participants diagnosed with bipolar disorder with onset within 5 years. Impact of treatment at six and twelve months post baseline on potential mediators (mood appraisal, growth and self-concept) for changes in personal recovery, social functioning and quality of life outcomes were first assessed. Mediation effects were evaluated on each outcome for mediators significantly impacted by treatment.ResultsRfT had a significant impact on positive self-appraisal and stigma at 12 months and self-esteem and post-trauma growth at six months. Both self-esteem and post-trauma growth significantly mediated the effect of RfT on personal recovery at six months follow-up.LimitationsThis is a relatively small study which was not originally powered to test for exploratory mediation effects.ConclusionsImprovements in personal recovery following RfT are linked to improvements in personal growth and self-esteem. This mediation relationship was not apparent for functioning or quality of life.
AB - BackgroundRecovery focused therapy has been shown to improve recovery outcomes in individuals with recent onset bipolar disorder. However the process by which this is achieved is unclear. This paper therefore examines potential mediators of this effect using data from a randomised controlled trial comparing recovery focused therapy with treatment as usual (ISRCTN43062149).MethodsA single-blind randomised controlled trial compared treatment as usual (TAU) with recovery-focused therapy (RfT) plus TAU (n = 67) in participants diagnosed with bipolar disorder with onset within 5 years. Impact of treatment at six and twelve months post baseline on potential mediators (mood appraisal, growth and self-concept) for changes in personal recovery, social functioning and quality of life outcomes were first assessed. Mediation effects were evaluated on each outcome for mediators significantly impacted by treatment.ResultsRfT had a significant impact on positive self-appraisal and stigma at 12 months and self-esteem and post-trauma growth at six months. Both self-esteem and post-trauma growth significantly mediated the effect of RfT on personal recovery at six months follow-up.LimitationsThis is a relatively small study which was not originally powered to test for exploratory mediation effects.ConclusionsImprovements in personal recovery following RfT are linked to improvements in personal growth and self-esteem. This mediation relationship was not apparent for functioning or quality of life.
KW - Bipolar disorder Personal recovery Recovery Mediation Appraisal Self-esteem
KW - Growth
U2 - 10.1016/j.jadr.2021.100175
DO - 10.1016/j.jadr.2021.100175
M3 - Journal article
VL - 5
SP - 1
EP - 6
JO - journal of affective disorders reports
JF - journal of affective disorders reports
SN - 2666-9153
M1 - 100175
ER -