This paper examines the dimension of mediation in the post-Internet condition through the post-Internet art medium. In the post-Internet condition, human and non-human actors, humans and machines, networks, algorithms and technologies, co-create conditions of life in a hybrid and liquid state of mediation. The paper discusses three important areas of mediatisation as highlights and indicators of the hybrid and multifaceted character of mediation post-Internet. These are mediated publicness, mediated self and mediated trust. The artworks discussed in this paper help illuminate the dynamics, tensions and experiences of contemporary mediation and act as examples of how important the role of mediation is in our understanding of the world and of ourselves in it and how vital it is to continue to explore and critically engage with its processes.