Home > Research > Publications & Outputs > Microbial evolution, diversity, and ecology


Text available via DOI:

View graph of relations

Microbial evolution, diversity, and ecology: A decade of ribosomal RNA analysis of uncultivated microorganisms

Research output: Contribution to Journal/MagazineJournal articlepeer-review

<mark>Journal publication date</mark>31/01/1998
<mark>Journal</mark>Microbial Ecology
Issue number1
Number of pages21
Pages (from-to)1-21
Publication StatusPublished
<mark>Original language</mark>English


The application of molecular biological methods to study the diversity and ecology of microorganisms in natural environments has been practiced since the mid-1980s. Since that time many new insights into the composition of uncultivated microbial communities have been gained. Whole groups of organisms that are only known from molecular sequences are now believed to be quantitatively significant in many environments. Molecular methods have also allowed characterization of many long-recognized but poorly understood organisms. These organisms have eluded laboratory cultivation and, hence, have remained enigmatic. This review provides an outline of the main methods used in molecular microbial ecology, and their limitations. Some discoveries, made through the application of molecular biological methods, are highlighted, with reference to morphologically distinctive, uncultivated bacteria; an important biotechnological process (wastewater treatment); and symbiotic relationships between Bacteria, Archaea and Eukarya.