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    Rights statement: ©American Psychological Association, 2021. This paper is not the copy of record and may not exactly replicate the authoritative document published in the APA journal. Please do not copy or cite without author's permission. The final article is available, upon publication, at: 10.1037/ccp0000684

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Mindfulness-Based Online Intervention to Improve Quality of Life in Late-Stage Bipolar Disorder: A Randomized Clinical Trial

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Mindfulness-Based Online Intervention to Improve Quality of Life in Late-Stage Bipolar Disorder : A Randomized Clinical Trial. / Murray, G.; Thomas, N.; Michalak, E.E. et al.

In: Journal of Consulting and Clinical Psychology, Vol. 89, No. 10, 31.10.2021, p. 830-844.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Murray, G, Thomas, N, Michalak, EE, Jones, SH, Lapsley, S, Bowe, SJ, Foley, F, Fletcher, K, Perich, T, Johnson, SL, Cotton, S, Berk, L, Mihalopoulos, C, Kyrios, M & Berk, M 2021, 'Mindfulness-Based Online Intervention to Improve Quality of Life in Late-Stage Bipolar Disorder: A Randomized Clinical Trial', Journal of Consulting and Clinical Psychology, vol. 89, no. 10, pp. 830-844. https://doi.org/10.1037/ccp0000684

APA

Murray, G., Thomas, N., Michalak, E. E., Jones, S. H., Lapsley, S., Bowe, S. J., Foley, F., Fletcher, K., Perich, T., Johnson, S. L., Cotton, S., Berk, L., Mihalopoulos, C., Kyrios, M., & Berk, M. (2021). Mindfulness-Based Online Intervention to Improve Quality of Life in Late-Stage Bipolar Disorder: A Randomized Clinical Trial. Journal of Consulting and Clinical Psychology, 89(10), 830-844. https://doi.org/10.1037/ccp0000684

Vancouver

Murray G, Thomas N, Michalak EE, Jones SH, Lapsley S, Bowe SJ et al. Mindfulness-Based Online Intervention to Improve Quality of Life in Late-Stage Bipolar Disorder: A Randomized Clinical Trial. Journal of Consulting and Clinical Psychology. 2021 Oct 31;89(10):830-844. doi: 10.1037/ccp0000684

Author

Murray, G. ; Thomas, N. ; Michalak, E.E. et al. / Mindfulness-Based Online Intervention to Improve Quality of Life in Late-Stage Bipolar Disorder : A Randomized Clinical Trial. In: Journal of Consulting and Clinical Psychology. 2021 ; Vol. 89, No. 10. pp. 830-844.

Bibtex

@article{d9f67991c7a74c28966db52e5147583b,
title = "Mindfulness-Based Online Intervention to Improve Quality of Life in Late-Stage Bipolar Disorder: A Randomized Clinical Trial",
abstract = "Objective: Adjunctive psychological interventions improve outcomes in bipolar disorder (BD), but people in latter stages likely have different clinical needs. The objective here was to test the hypothesis that for people with ≥⃒ 10 episodes of BD, a brief online mindfulness-based intervention (ORBIT 2.0) improves quality of life (QoL) relative to a Psychoeducation control. Method: A rater-masked, pragmatic superiority randomized clinical trial compared ORBIT 2.0 with active control. Both interventions were 5-week coach-supported programs with treatment as usual continued. Inclusion criteria included age 18–65 years, confirmed diagnosis of BD, and history of ≱ 10 episodes. Measures were collected at baseline, postintervention, and 3 and 6-month follow-ups. The main outcome was QoL, measured on the Brief Quality of Life in Bipolar Disorder (Brief QoL.BD) at 5 weeks, using intentiont treat analyses. Results: Among N = 302 randomized participants, the primary hypothesis was not supported (Treatment × Time β = −0.69, 95% CI [−2.69, 1.31], p =.50). The main effect of Time was not significant in either condition, indicating no improvement in either group. Recruitment was feasible, the platform was safe, both interventions were highly acceptable, but usage was suboptimal. Post hoc analyses found both interventions effective for participants not in remission from depression at baseline.Conclusions: In people with late-stage BD, an online mindfulness-based intervention was not superior to psychoeducational control in improving QoL. Online delivery was found to be safe and acceptable.Future interventions may need to be higher intensity, address engagement challenges, and target more symptomatic individuals ",
keywords = "bipolar disorder, mindfulness, online, quality of life, stage of illness",
author = "G. Murray and N. Thomas and E.E. Michalak and S.H. Jones and S. Lapsley and S.J. Bowe and F. Foley and K. Fletcher and T. Perich and S.L. Johnson and S. Cotton and L. Berk and C. Mihalopoulos and M. Kyrios and M. Berk",
note = "{\textcopyright}American Psychological Association, 2021. This paper is not the copy of record and may not exactly replicate the authoritative document published in the APA journal. Please do not copy or cite without author's permission. The final article is available, upon publication, at: 10.1037/ccp0000684",
year = "2021",
month = oct,
day = "31",
doi = "10.1037/ccp0000684",
language = "English",
volume = "89",
pages = "830--844",
journal = "Journal of Consulting and Clinical Psychology",
issn = "0022-006X",
publisher = "American Psychological Association Inc.",
number = "10",

}

RIS

TY - JOUR

T1 - Mindfulness-Based Online Intervention to Improve Quality of Life in Late-Stage Bipolar Disorder

T2 - A Randomized Clinical Trial

AU - Murray, G.

AU - Thomas, N.

AU - Michalak, E.E.

AU - Jones, S.H.

AU - Lapsley, S.

AU - Bowe, S.J.

AU - Foley, F.

AU - Fletcher, K.

AU - Perich, T.

AU - Johnson, S.L.

AU - Cotton, S.

AU - Berk, L.

AU - Mihalopoulos, C.

AU - Kyrios, M.

AU - Berk, M.

N1 - ©American Psychological Association, 2021. This paper is not the copy of record and may not exactly replicate the authoritative document published in the APA journal. Please do not copy or cite without author's permission. The final article is available, upon publication, at: 10.1037/ccp0000684

PY - 2021/10/31

Y1 - 2021/10/31

N2 - Objective: Adjunctive psychological interventions improve outcomes in bipolar disorder (BD), but people in latter stages likely have different clinical needs. The objective here was to test the hypothesis that for people with ≥⃒ 10 episodes of BD, a brief online mindfulness-based intervention (ORBIT 2.0) improves quality of life (QoL) relative to a Psychoeducation control. Method: A rater-masked, pragmatic superiority randomized clinical trial compared ORBIT 2.0 with active control. Both interventions were 5-week coach-supported programs with treatment as usual continued. Inclusion criteria included age 18–65 years, confirmed diagnosis of BD, and history of ≱ 10 episodes. Measures were collected at baseline, postintervention, and 3 and 6-month follow-ups. The main outcome was QoL, measured on the Brief Quality of Life in Bipolar Disorder (Brief QoL.BD) at 5 weeks, using intentiont treat analyses. Results: Among N = 302 randomized participants, the primary hypothesis was not supported (Treatment × Time β = −0.69, 95% CI [−2.69, 1.31], p =.50). The main effect of Time was not significant in either condition, indicating no improvement in either group. Recruitment was feasible, the platform was safe, both interventions were highly acceptable, but usage was suboptimal. Post hoc analyses found both interventions effective for participants not in remission from depression at baseline.Conclusions: In people with late-stage BD, an online mindfulness-based intervention was not superior to psychoeducational control in improving QoL. Online delivery was found to be safe and acceptable.Future interventions may need to be higher intensity, address engagement challenges, and target more symptomatic individuals

AB - Objective: Adjunctive psychological interventions improve outcomes in bipolar disorder (BD), but people in latter stages likely have different clinical needs. The objective here was to test the hypothesis that for people with ≥⃒ 10 episodes of BD, a brief online mindfulness-based intervention (ORBIT 2.0) improves quality of life (QoL) relative to a Psychoeducation control. Method: A rater-masked, pragmatic superiority randomized clinical trial compared ORBIT 2.0 with active control. Both interventions were 5-week coach-supported programs with treatment as usual continued. Inclusion criteria included age 18–65 years, confirmed diagnosis of BD, and history of ≱ 10 episodes. Measures were collected at baseline, postintervention, and 3 and 6-month follow-ups. The main outcome was QoL, measured on the Brief Quality of Life in Bipolar Disorder (Brief QoL.BD) at 5 weeks, using intentiont treat analyses. Results: Among N = 302 randomized participants, the primary hypothesis was not supported (Treatment × Time β = −0.69, 95% CI [−2.69, 1.31], p =.50). The main effect of Time was not significant in either condition, indicating no improvement in either group. Recruitment was feasible, the platform was safe, both interventions were highly acceptable, but usage was suboptimal. Post hoc analyses found both interventions effective for participants not in remission from depression at baseline.Conclusions: In people with late-stage BD, an online mindfulness-based intervention was not superior to psychoeducational control in improving QoL. Online delivery was found to be safe and acceptable.Future interventions may need to be higher intensity, address engagement challenges, and target more symptomatic individuals

KW - bipolar disorder

KW - mindfulness

KW - online

KW - quality of life

KW - stage of illness

U2 - 10.1037/ccp0000684

DO - 10.1037/ccp0000684

M3 - Journal article

VL - 89

SP - 830

EP - 844

JO - Journal of Consulting and Clinical Psychology

JF - Journal of Consulting and Clinical Psychology

SN - 0022-006X

IS - 10

ER -