Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - mmm
T2 - an R package for analyzing multivariate longitudinal data with multivariate marginal models.
AU - Asar, Özgür
AU - Ilk, Ozlem
PY - 2013/12
Y1 - 2013/12
N2 - Modeling multivariate longitudinal data has many challenges in terms of both statistical and computational aspects. Statistical challenges occur due to complex dependence structures. Computational challenges are due to the complex algorithms, the use of numerical methods, and potential convergence problems. Therefore, there is a lack of software for such data. This paper introduces an R package mmm prepared for marginal modeling of multivariate longitudinal data. Parameter estimations are achieved by generalized estimating equations approach. A real life data set is applied to illustrate the core features of the package, and sample R code snippets are provided. It is shown that the multivariate marginal models considered in this paper and mmm are valid for binary, continuous and count multivariate longitudinal responses.
AB - Modeling multivariate longitudinal data has many challenges in terms of both statistical and computational aspects. Statistical challenges occur due to complex dependence structures. Computational challenges are due to the complex algorithms, the use of numerical methods, and potential convergence problems. Therefore, there is a lack of software for such data. This paper introduces an R package mmm prepared for marginal modeling of multivariate longitudinal data. Parameter estimations are achieved by generalized estimating equations approach. A real life data set is applied to illustrate the core features of the package, and sample R code snippets are provided. It is shown that the multivariate marginal models considered in this paper and mmm are valid for binary, continuous and count multivariate longitudinal responses.
KW - Correlated data
KW - Multiple outcomes
KW - Medical studies
KW - Package presentation
KW - Population-averaged inference
KW - Statistical software
U2 - 10.1016/j.cmpb.2013.07.022
DO - 10.1016/j.cmpb.2013.07.022
M3 - Journal article
VL - 112
SP - 649
EP - 654
JO - Computer Methods and Programs in Biomedicine
JF - Computer Methods and Programs in Biomedicine
SN - 1872-7565
IS - 3
ER -