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Modelled and measured arsenic exposure around a power station in Slovakia

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Modelled and measured arsenic exposure around a power station in Slovakia. / Keegan, T. J.; Nieuwenhuijsen, M. J.; Pesch, B. et al.
In: Applied Geochemistry, Vol. 27, No. 5, 05.2012, p. 1013-1019.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Keegan, TJ, Nieuwenhuijsen, MJ, Pesch, B, Ranft, U, Thornton, I & EXPASCAN Study Grp 2012, 'Modelled and measured arsenic exposure around a power station in Slovakia', Applied Geochemistry, vol. 27, no. 5, pp. 1013-1019. https://doi.org/10.1016/j.apgeochem.2011.11.006

APA

Keegan, T. J., Nieuwenhuijsen, M. J., Pesch, B., Ranft, U., Thornton, I., & EXPASCAN Study Grp (2012). Modelled and measured arsenic exposure around a power station in Slovakia. Applied Geochemistry, 27(5), 1013-1019. https://doi.org/10.1016/j.apgeochem.2011.11.006

Vancouver

Keegan TJ, Nieuwenhuijsen MJ, Pesch B, Ranft U, Thornton I, EXPASCAN Study Grp. Modelled and measured arsenic exposure around a power station in Slovakia. Applied Geochemistry. 2012 May;27(5):1013-1019. Epub 2011 May 1. doi: 10.1016/j.apgeochem.2011.11.006

Author

Keegan, T. J. ; Nieuwenhuijsen, M. J. ; Pesch, B. et al. / Modelled and measured arsenic exposure around a power station in Slovakia. In: Applied Geochemistry. 2012 ; Vol. 27, No. 5. pp. 1013-1019.

Bibtex

@article{b36c8da9166d4fd3846c3a5f46b3ab0c,
title = "Modelled and measured arsenic exposure around a power station in Slovakia",
abstract = "In 1999-2000 an epidemiological study was carried out to investigate arsenic exposure and risk of nonmelanoma skin cancer in the population around a power station in Slovakia. As part of the exposure assessment for that study, markers of physiological exposure to arsenic (urinary arsenic and nail arsenic) and measures of environmental arsenic were taken. Residential history and arsenic emissions were combined in a measure used to classify the study population's exposure. Here, we take a model designed to estimate the daily arsenic absorption and urinary arsenic excretion developed by the US EPA and compare its output to the values for measured urinary arsenic, measured environmental arsenic and modelled food arsenic used in the previous study. We found that the US EPA model underestimated arsenic exposure in this population. Potential misclassification compared to the exposure used previously was also quantified, with poor agreement between a measured biomarker of current arsenic exposure and modelled estimates of arsenic uptake and excretion. (C) 2011 Published by Elsevier Ltd.",
author = "Keegan, {T. J.} and Nieuwenhuijsen, {M. J.} and B. Pesch and U. Ranft and I. Thornton and {EXPASCAN Study Grp}",
year = "2012",
month = may,
doi = "10.1016/j.apgeochem.2011.11.006",
language = "English",
volume = "27",
pages = "1013--1019",
journal = "Applied Geochemistry",
publisher = "Elsevier Limited",
number = "5",

}

RIS

TY - JOUR

T1 - Modelled and measured arsenic exposure around a power station in Slovakia

AU - Keegan, T. J.

AU - Nieuwenhuijsen, M. J.

AU - Pesch, B.

AU - Ranft, U.

AU - Thornton, I.

AU - EXPASCAN Study Grp

PY - 2012/5

Y1 - 2012/5

N2 - In 1999-2000 an epidemiological study was carried out to investigate arsenic exposure and risk of nonmelanoma skin cancer in the population around a power station in Slovakia. As part of the exposure assessment for that study, markers of physiological exposure to arsenic (urinary arsenic and nail arsenic) and measures of environmental arsenic were taken. Residential history and arsenic emissions were combined in a measure used to classify the study population's exposure. Here, we take a model designed to estimate the daily arsenic absorption and urinary arsenic excretion developed by the US EPA and compare its output to the values for measured urinary arsenic, measured environmental arsenic and modelled food arsenic used in the previous study. We found that the US EPA model underestimated arsenic exposure in this population. Potential misclassification compared to the exposure used previously was also quantified, with poor agreement between a measured biomarker of current arsenic exposure and modelled estimates of arsenic uptake and excretion. (C) 2011 Published by Elsevier Ltd.

AB - In 1999-2000 an epidemiological study was carried out to investigate arsenic exposure and risk of nonmelanoma skin cancer in the population around a power station in Slovakia. As part of the exposure assessment for that study, markers of physiological exposure to arsenic (urinary arsenic and nail arsenic) and measures of environmental arsenic were taken. Residential history and arsenic emissions were combined in a measure used to classify the study population's exposure. Here, we take a model designed to estimate the daily arsenic absorption and urinary arsenic excretion developed by the US EPA and compare its output to the values for measured urinary arsenic, measured environmental arsenic and modelled food arsenic used in the previous study. We found that the US EPA model underestimated arsenic exposure in this population. Potential misclassification compared to the exposure used previously was also quantified, with poor agreement between a measured biomarker of current arsenic exposure and modelled estimates of arsenic uptake and excretion. (C) 2011 Published by Elsevier Ltd.

U2 - 10.1016/j.apgeochem.2011.11.006

DO - 10.1016/j.apgeochem.2011.11.006

M3 - Journal article

VL - 27

SP - 1013

EP - 1019

JO - Applied Geochemistry

JF - Applied Geochemistry

IS - 5

ER -