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Mycobacterium avium subspecies paratuberculosis: human exposure through environmental and domestic aerosols

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Mycobacterium avium subspecies paratuberculosis : human exposure through environmental and domestic aerosols. / Rhodes, Glenn; Richardson, Hollian; Hermon-Taylor, John; Weightman, Andrew; Higham, Andrew; Pickup, Roger.

In: Pathogens, Vol. 3, No. 3, 14.07.2014, p. 577-595.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Rhodes, G, Richardson, H, Hermon-Taylor, J, Weightman, A, Higham, A & Pickup, R 2014, 'Mycobacterium avium subspecies paratuberculosis: human exposure through environmental and domestic aerosols', Pathogens, vol. 3, no. 3, pp. 577-595. https://doi.org/10.3390/pathogens3030577

APA

Rhodes, G., Richardson, H., Hermon-Taylor, J., Weightman, A., Higham, A., & Pickup, R. (2014). Mycobacterium avium subspecies paratuberculosis: human exposure through environmental and domestic aerosols. Pathogens, 3(3), 577-595. https://doi.org/10.3390/pathogens3030577

Vancouver

Author

Rhodes, Glenn ; Richardson, Hollian ; Hermon-Taylor, John ; Weightman, Andrew ; Higham, Andrew ; Pickup, Roger. / Mycobacterium avium subspecies paratuberculosis : human exposure through environmental and domestic aerosols. In: Pathogens. 2014 ; Vol. 3, No. 3. pp. 577-595.

Bibtex

@article{dc899e61f2244f439a6f9b9d4f705a9f,
title = "Mycobacterium avium subspecies paratuberculosis: human exposure through environmental and domestic aerosols",
abstract = "Mycobacterium avium subspecies paratuberculosis (Map) causes Johne{\textquoteright}s disease in animals and is significantly associated with Crohn{\textquoteright}s disease (CD) in humans. Our previous studies have shown Map to be present in U.K. rivers due to land deposition from chronic livestock infection and runoff driven by rainfall. The epidemiology of CD in Cardiff showed a significant association with the River Taff, in which Map can be detected on a regular basis. We have previously hypothesized that aerosols from the river might influence the epidemiology of CD. In this preliminary study, we detected Map by quantitative PCR in one of five aerosol samples collected above the River Taff. In addition, we examined domestic showers from different regions in the U.K. and detected Map in three out of 30 independent samples. In detecting Map in river aerosols and those from domestic showers, this is the first study to provide evidence that aerosols are an exposure route for Map to humans and may play a role in the epidemiology of CD.",
keywords = "Mycobacterium avium subspecies paratuberculosis, Crohn{\textquoteright}s disease , aerosols , rivers , domestic showers , exposure",
author = "Glenn Rhodes and Hollian Richardson and John Hermon-Taylor and Andrew Weightman and Andrew Higham and Roger Pickup",
note = "This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.",
year = "2014",
month = jul,
day = "14",
doi = "10.3390/pathogens3030577",
language = "English",
volume = "3",
pages = "577--595",
journal = "Pathogens",
issn = "2076-0817",
publisher = "MDPI AG",
number = "3",

}

RIS

TY - JOUR

T1 - Mycobacterium avium subspecies paratuberculosis

T2 - human exposure through environmental and domestic aerosols

AU - Rhodes, Glenn

AU - Richardson, Hollian

AU - Hermon-Taylor, John

AU - Weightman, Andrew

AU - Higham, Andrew

AU - Pickup, Roger

N1 - This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PY - 2014/7/14

Y1 - 2014/7/14

N2 - Mycobacterium avium subspecies paratuberculosis (Map) causes Johne’s disease in animals and is significantly associated with Crohn’s disease (CD) in humans. Our previous studies have shown Map to be present in U.K. rivers due to land deposition from chronic livestock infection and runoff driven by rainfall. The epidemiology of CD in Cardiff showed a significant association with the River Taff, in which Map can be detected on a regular basis. We have previously hypothesized that aerosols from the river might influence the epidemiology of CD. In this preliminary study, we detected Map by quantitative PCR in one of five aerosol samples collected above the River Taff. In addition, we examined domestic showers from different regions in the U.K. and detected Map in three out of 30 independent samples. In detecting Map in river aerosols and those from domestic showers, this is the first study to provide evidence that aerosols are an exposure route for Map to humans and may play a role in the epidemiology of CD.

AB - Mycobacterium avium subspecies paratuberculosis (Map) causes Johne’s disease in animals and is significantly associated with Crohn’s disease (CD) in humans. Our previous studies have shown Map to be present in U.K. rivers due to land deposition from chronic livestock infection and runoff driven by rainfall. The epidemiology of CD in Cardiff showed a significant association with the River Taff, in which Map can be detected on a regular basis. We have previously hypothesized that aerosols from the river might influence the epidemiology of CD. In this preliminary study, we detected Map by quantitative PCR in one of five aerosol samples collected above the River Taff. In addition, we examined domestic showers from different regions in the U.K. and detected Map in three out of 30 independent samples. In detecting Map in river aerosols and those from domestic showers, this is the first study to provide evidence that aerosols are an exposure route for Map to humans and may play a role in the epidemiology of CD.

KW - Mycobacterium avium subspecies paratuberculosis

KW - Crohn’s disease

KW - aerosols

KW - rivers

KW - domestic showers

KW - exposure

U2 - 10.3390/pathogens3030577

DO - 10.3390/pathogens3030577

M3 - Journal article

VL - 3

SP - 577

EP - 595

JO - Pathogens

JF - Pathogens

SN - 2076-0817

IS - 3

ER -