This paper studies a gas-gas multi nozzle annular jet pump, a variant of the annular jet pump configuration. The multi-nozzle jet pump injects the motive fluid through discrete nozzles distributed around the pump bore. Due to their orientation the jets induce swirl downstream of the injection nozzles. A swirling flow is reported in several studies to improve the efficiency of annular jet pumps by improving the mixing between fluids. Two pump designs with differing nozzles orientations are investigated using the commercial CFD code ANSYS FLUENT with results compared to experimental data. The study explores the sensitivity of grid-independent solutions to selected RANs turbulence models. A design of experiments based on the nozzle orientation of the pumps is then undertaken to assess the effect on performance.