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Neuropeptides in the rat claustrum - An immunohistochemical detection

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  • Anna Lipiec-Borowicz
  • Artur Pałasz
  • Aleksandra Suszka-Świtek
  • Łukasz Filipczyk
  • Alessandra Della Vecchia
  • John J Worthington
  • Aneta Piwowarczyk-Nowak
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Article number152156
<mark>Journal publication date</mark>30/04/2024
<mark>Journal</mark>Acta histochemica
Issue number3
Volume126
Publication StatusPublished
Early online date20/03/24
<mark>Original language</mark>English

Abstract

Neuropeptides are involved in numerous brain activities and are responsible for a wide spectrum of higher mental functions. The main purpose of this outline structural qualitative study was to identify the possible immunoreactivity of classical neuropeptides, as well as novel ones such as nesfatin-1, phoenixin (PNX), spexin (SPX), neuromedin U (NMU) and respective receptors within the rat claustrum for the first time. The study shows the novel identification of peptidergic neurotransmission in the rat claustrum which potentially implicates a contribution of this neuropeptide to numerous central neurosecretory mechanisms.