Emerging glass structures, which frequently use laminated glass (LG) as load bearing elements, see a significant rise in recent decade. Existing analytical solutions for LG under impact present limitation when introduced into structural LG products, as structural LG having more glass plies and soft polymeric interlayers requires more accurate nonlinear analytical model. In this study, a nonlinear analytical model was proposed for the simply supported square structural LG subjected to hard body impact. The motion equations were established based on a third order shear deformation theory and von Kármán nonlinear strain–displacement relationship. Based on a two-step perturbation method, the solutions of the motion equations were obtained. The fourth-order Runge–Kutta method was used to capture the impact force variation. Drop weight impact tests with increasing impact velocity, were conducted to record the impact force of LG panels before breakage. Eighteen LG panels with PVB or SG interlayers were tested. Through analysing the fracture initiation from high speed photos as well as the impact force variation in the impact attempt causing fracture, certain feature of the experimental impact force response was determined to be validated with analytical prediction. The validation results show that the proposed model can well reproduce the examined feature and achieve satisfactory impact force response. Case study was then designed to investigate the influence due to the safety windows film on reducing the pre-crack impact response. The effective thickness of LG based on the equivalence of indentation was also proposed for the hard body impact.