TY - JOUR

T1 - Oral corticosteroids for bronchiectasis (stable and acute exacerbations)

AU - Lasserson, Toby J.

AU - Holt, Kay

AU - Milan, Stephen

AU - Greenstone, Michael

PY - 2001/4/23

Y1 - 2001/4/23

N2 - AbstractBackgroundInflammation plays a significant role in the pathophysiology of bronchiectasis. Two small studies have shown small benefits from inhaled corticosteroids and oral corticosteroids may be of benefit in bronchiectasisObjectivesTo determine the efficacy of oral corticosteroids in acute and stable bronchiectasisSearch methodsThe Cochrane Airways Group Specialised Register was searched and bibliographies of retrieved papers were checked. Searches are current as of May 2011.Selection criteriaOnly randomised controlled trials were consideredData collection and analysisNo trials met the inclusion criteria for the review.Main resultsNo randomised controlled trials were identifiedAuthors' conclusionsThere are no randomised trials upon which to base recommendations about the use of oral corticosteroids in acute or stable bronchiectasis. Plain language summaryOral corticosteroids for bronchiectasis (stable and acute exacerbations)Bronchiectasis is a chronic respiratory disease. People with the condition experience difficulty in clearing mucus from their lungs, leaving them prone to infections. Oral steroids have a place in the management of acute and severe asthma. In bronchiectasis, inhaled steroids have small benefits but there is no evidence for or against the use of oral steroids for this condition.

AB - AbstractBackgroundInflammation plays a significant role in the pathophysiology of bronchiectasis. Two small studies have shown small benefits from inhaled corticosteroids and oral corticosteroids may be of benefit in bronchiectasisObjectivesTo determine the efficacy of oral corticosteroids in acute and stable bronchiectasisSearch methodsThe Cochrane Airways Group Specialised Register was searched and bibliographies of retrieved papers were checked. Searches are current as of May 2011.Selection criteriaOnly randomised controlled trials were consideredData collection and analysisNo trials met the inclusion criteria for the review.Main resultsNo randomised controlled trials were identifiedAuthors' conclusionsThere are no randomised trials upon which to base recommendations about the use of oral corticosteroids in acute or stable bronchiectasis. Plain language summaryOral corticosteroids for bronchiectasis (stable and acute exacerbations)Bronchiectasis is a chronic respiratory disease. People with the condition experience difficulty in clearing mucus from their lungs, leaving them prone to infections. Oral steroids have a place in the management of acute and severe asthma. In bronchiectasis, inhaled steroids have small benefits but there is no evidence for or against the use of oral steroids for this condition.

U2 - 10.1002/14651858.CD002162

DO - 10.1002/14651858.CD002162

M3 - Journal article

JO - Cochrane Database of Systematic Reviews

JF - Cochrane Database of Systematic Reviews

SN - 1469-493X

ER -