TY - JOUR

T1 - Periostin

T2 - Immunomodulatory Effects on Oral Diseases

AU - Khurshid, Z.

AU - Mali, M.

AU - Adanir, N.

AU - Zafar, M.S.

AU - Khan, R.S.

AU - Latif, M.

PY - 2020/7/20

Y1 - 2020/7/20

N2 - Periostin is a microcellular adapter protein. It plays a wide range of essential roles during the development and in immunomodulation. Periostin is a prominent contributor during the process of angiogenesis, tumorigenesis, and cardiac repair. It is expressed in periodontal ligaments, tendons, skin, adipose tissues, muscle, and bone. This is a protein-based biomolecule that has the diagnostic and monitoring capability and potentially be used as a biomarker to detect physiological and pathological conditions. The aim of the present review was to explore the periostin morphology and associated structural features. In addition, periostin's immunomodulatory effects and associated biomarkers in context of oral diseases have been discussed.

AB - Periostin is a microcellular adapter protein. It plays a wide range of essential roles during the development and in immunomodulation. Periostin is a prominent contributor during the process of angiogenesis, tumorigenesis, and cardiac repair. It is expressed in periodontal ligaments, tendons, skin, adipose tissues, muscle, and bone. This is a protein-based biomolecule that has the diagnostic and monitoring capability and potentially be used as a biomarker to detect physiological and pathological conditions. The aim of the present review was to explore the periostin morphology and associated structural features. In addition, periostin's immunomodulatory effects and associated biomarkers in context of oral diseases have been discussed.

KW - biomarkers

KW - health

KW - oral

KW - periostin and periodontitis

U2 - 10.1055/s-0040-1714037

DO - 10.1055/s-0040-1714037

M3 - Journal article

VL - 14

JO - European Journal of Dentistry

JF - European Journal of Dentistry

IS - 3

ER -