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    Rights statement: Open Access funded by Engineering and Physical Sciences Research Council Under a Creative Commons license

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Pharmaceutical film coating catalogue for spectral-domain optical coherence tomography

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Pharmaceutical film coating catalogue for spectral-domain optical coherence tomography. / Lin, Hungyen; Dong, Yue; Markl, Daniel et al.
In: Journal of Pharmaceutical Sciences, Vol. 106, No. 10, 10.2017, p. 3171-3176.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Lin, H, Dong, Y, Markl, D, Zhang, Z, Shen, Y & Zeitler, JA 2017, 'Pharmaceutical film coating catalogue for spectral-domain optical coherence tomography', Journal of Pharmaceutical Sciences, vol. 106, no. 10, pp. 3171-3176. https://doi.org/10.1016/j.xphs.2017.05.032

APA

Lin, H., Dong, Y., Markl, D., Zhang, Z., Shen, Y., & Zeitler, J. A. (2017). Pharmaceutical film coating catalogue for spectral-domain optical coherence tomography. Journal of Pharmaceutical Sciences, 106(10), 3171-3176. https://doi.org/10.1016/j.xphs.2017.05.032

Vancouver

Lin H, Dong Y, Markl D, Zhang Z, Shen Y, Zeitler JA. Pharmaceutical film coating catalogue for spectral-domain optical coherence tomography. Journal of Pharmaceutical Sciences. 2017 Oct;106(10):3171-3176. Epub 2017 Jun 15. doi: 10.1016/j.xphs.2017.05.032

Author

Lin, Hungyen ; Dong, Yue ; Markl, Daniel et al. / Pharmaceutical film coating catalogue for spectral-domain optical coherence tomography. In: Journal of Pharmaceutical Sciences. 2017 ; Vol. 106, No. 10. pp. 3171-3176.

Bibtex

@article{02df9e3692c84885a2cf9f0d1e63bb7d,
title = "Pharmaceutical film coating catalogue for spectral-domain optical coherence tomography",
abstract = "Optical coherence tomography (OCT) has recently been demonstrated to measure the film coating thickness of pharmaceutical tablets and pellets directly. The results enable the analysis of inter- and intra-tablet coating variability at an off-line and in-line setting. To date, only a few coating formulations have been tried and there is very little information on the applicability of OCT to other coatings. As it is well documented that optical methods including OCT are prone to scattering leading to limited penetration, some pharmaceutical coatings may not be measurable altogether. This study presents OCT measurements of 22 different common coatings for the assessment of OCT applicability.",
keywords = "optical coherence tomography, pharmaceutical film coating, coating thickness",
author = "Hungyen Lin and Yue Dong and Daniel Markl and Zijian Zhang and Yaochun Shen and Zeitler, {J. Axel}",
note = "Open Access funded by Engineering and Physical Sciences Research Council Under a Creative Commons license",
year = "2017",
month = oct,
doi = "10.1016/j.xphs.2017.05.032",
language = "English",
volume = "106",
pages = "3171--3176",
journal = "Journal of Pharmaceutical Sciences",
issn = "0022-3549",
publisher = "John Wiley and Sons Inc.",
number = "10",

}

RIS

TY - JOUR

T1 - Pharmaceutical film coating catalogue for spectral-domain optical coherence tomography

AU - Lin, Hungyen

AU - Dong, Yue

AU - Markl, Daniel

AU - Zhang, Zijian

AU - Shen, Yaochun

AU - Zeitler, J. Axel

N1 - Open Access funded by Engineering and Physical Sciences Research Council Under a Creative Commons license

PY - 2017/10

Y1 - 2017/10

N2 - Optical coherence tomography (OCT) has recently been demonstrated to measure the film coating thickness of pharmaceutical tablets and pellets directly. The results enable the analysis of inter- and intra-tablet coating variability at an off-line and in-line setting. To date, only a few coating formulations have been tried and there is very little information on the applicability of OCT to other coatings. As it is well documented that optical methods including OCT are prone to scattering leading to limited penetration, some pharmaceutical coatings may not be measurable altogether. This study presents OCT measurements of 22 different common coatings for the assessment of OCT applicability.

AB - Optical coherence tomography (OCT) has recently been demonstrated to measure the film coating thickness of pharmaceutical tablets and pellets directly. The results enable the analysis of inter- and intra-tablet coating variability at an off-line and in-line setting. To date, only a few coating formulations have been tried and there is very little information on the applicability of OCT to other coatings. As it is well documented that optical methods including OCT are prone to scattering leading to limited penetration, some pharmaceutical coatings may not be measurable altogether. This study presents OCT measurements of 22 different common coatings for the assessment of OCT applicability.

KW - optical coherence tomography

KW - pharmaceutical film coating

KW - coating thickness

U2 - 10.1016/j.xphs.2017.05.032

DO - 10.1016/j.xphs.2017.05.032

M3 - Journal article

VL - 106

SP - 3171

EP - 3176

JO - Journal of Pharmaceutical Sciences

JF - Journal of Pharmaceutical Sciences

SN - 0022-3549

IS - 10

ER -