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Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Physical health comorbidities in older adults with bipolar disorder
T2 - A systematic review
AU - Warner, Aaron
AU - Holland, Carol
AU - Lobban, Fiona
AU - Tyler, Elizabeth
AU - Harvey, Daisy
AU - Newens, Connie
AU - Palmier-Claus, Jasper
PY - 2023/4/1
Y1 - 2023/4/1
N2 - To ascertain the prevalence and predictors of physical health comorbidities in older adults with bipolar disorder. The authors conducted a systematic review and narrative synthesis of peer-reviewed journal articles reporting on physical health comorbidities in older adults (aged ≥50) with a diagnosis of bipolar disorder. The Mixed Methods Appraisal Tool (MMAT) assessed study quality. 23 papers reporting on 19 studies met the inclusion criteria. The literature on diabetes, obesity and renal disease was inconclusive. There was some tentative evidence to higher rates of cardiovascular disease and some forms of cancer in older adults with bipolar disorder in comparison to the general population, but this requires further investigation. We identified no studies looking at oral health. The quality ratings of the identified research were generally low. Very few studies included a comparison sample from the general population or controlled for key covariates in their analysis. Existing literature provides tentative evidence that some physical health comorbidities are elevated in older adults with bipolar disorder. Clinicians should consider interventions that improve the physical health of this group, alongside the chronic mental health difficulties they experience. [Abstract copyright: Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.]
AB - To ascertain the prevalence and predictors of physical health comorbidities in older adults with bipolar disorder. The authors conducted a systematic review and narrative synthesis of peer-reviewed journal articles reporting on physical health comorbidities in older adults (aged ≥50) with a diagnosis of bipolar disorder. The Mixed Methods Appraisal Tool (MMAT) assessed study quality. 23 papers reporting on 19 studies met the inclusion criteria. The literature on diabetes, obesity and renal disease was inconclusive. There was some tentative evidence to higher rates of cardiovascular disease and some forms of cancer in older adults with bipolar disorder in comparison to the general population, but this requires further investigation. We identified no studies looking at oral health. The quality ratings of the identified research were generally low. Very few studies included a comparison sample from the general population or controlled for key covariates in their analysis. Existing literature provides tentative evidence that some physical health comorbidities are elevated in older adults with bipolar disorder. Clinicians should consider interventions that improve the physical health of this group, alongside the chronic mental health difficulties they experience. [Abstract copyright: Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.]
KW - Ageing
KW - Physical health - comorbidity
KW - Bipolar disorder
U2 - 10.1016/j.jad.2023.01.083
DO - 10.1016/j.jad.2023.01.083
M3 - Journal article
C2 - 36709829
VL - 326
SP - 232
EP - 242
JO - Journal of affective disorders
JF - Journal of affective disorders
SN - 0165-0327
ER -