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Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Physicochemical properties of freeze-dried bigel-based materials composed of sodium alginate/whey protein isolate hydrogel and ethylcellulose/sunflower oil oleogel
AU - Walendziak, Weronika
AU - Douglas, Timothy
AU - Kozlowska, Justyna
PY - 2025/4/14
Y1 - 2025/4/14
N2 - Freeze–drying bigels is a novel technique for developing functional materials for dermatological and cosmetic use, leveraging the benefits of two structured phases. This study optimized freeze–dried bigels composed of whey protein isolate (WPI)/sodium alginate/glycerin hydrogel and ethylcellulose (EC)/Span 80/sunflower oil oleogel at varying hydrogel/oleogel ratios. The materials showed swelling ratios from 50% to 255%, with higher values for a lower oleogel content and higher polymer concentration. The higher oleogel content extended the degradation from a few hours to 7 days. The polymer concentrations and hydrogel/oleogel ratios influenced Young’s modulus (1.25–3.7 MPa). Porosity varied from 35% to 58%, and density varied from 100 to 200 mg/mL. The residual moisture content (5% to 20%) increased with EC content and decreased with WPI and oleogel content. These findings underscore the role of polymer concentrations and phase ratios in tuning the physicochemical properties of freeze–dried gels, positioning them as promising biomaterials for skincare and cosmetic applications.
AB - Freeze–drying bigels is a novel technique for developing functional materials for dermatological and cosmetic use, leveraging the benefits of two structured phases. This study optimized freeze–dried bigels composed of whey protein isolate (WPI)/sodium alginate/glycerin hydrogel and ethylcellulose (EC)/Span 80/sunflower oil oleogel at varying hydrogel/oleogel ratios. The materials showed swelling ratios from 50% to 255%, with higher values for a lower oleogel content and higher polymer concentration. The higher oleogel content extended the degradation from a few hours to 7 days. The polymer concentrations and hydrogel/oleogel ratios influenced Young’s modulus (1.25–3.7 MPa). Porosity varied from 35% to 58%, and density varied from 100 to 200 mg/mL. The residual moisture content (5% to 20%) increased with EC content and decreased with WPI and oleogel content. These findings underscore the role of polymer concentrations and phase ratios in tuning the physicochemical properties of freeze–dried gels, positioning them as promising biomaterials for skincare and cosmetic applications.
U2 - 10.1021/acs.biomac.4c01677
DO - 10.1021/acs.biomac.4c01677
M3 - Journal article
VL - 26
SP - 2344
EP - 2355
JO - Biomacromolecules
JF - Biomacromolecules
SN - 1525-7797
IS - 4
ER -