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Preparation and investigation of nano-carbonated hydroxy apatite/polymer composite spongy scaffolds for biomedical applications

Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

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Preparation and investigation of nano-carbonated hydroxy apatite/polymer composite spongy scaffolds for biomedical applications. / Siddiqi, S.A.; Manzoor, F.; Azhar, U.; Jamal, A.; Tariq, M.; Anwar, M.S.; Saleem, M.; Chaudhry, A.A.; Rehman, I.U.; M., Laudon (Editor); B., Romanowicz (Editor).

TechConnect World Innovation Conference & Expo 2015. TechConnect, 2015. p. 270-273.

Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

Harvard

Siddiqi, SA, Manzoor, F, Azhar, U, Jamal, A, Tariq, M, Anwar, MS, Saleem, M, Chaudhry, AA, Rehman, IU, M., L (ed.) & B., R (ed.) 2015, Preparation and investigation of nano-carbonated hydroxy apatite/polymer composite spongy scaffolds for biomedical applications. in TechConnect World Innovation Conference & Expo 2015. TechConnect, pp. 270-273.

APA

Siddiqi, S. A., Manzoor, F., Azhar, U., Jamal, A., Tariq, M., Anwar, M. S., Saleem, M., Chaudhry, A. A., Rehman, I. U., M., L. (Ed.), & B., R. (Ed.) (2015). Preparation and investigation of nano-carbonated hydroxy apatite/polymer composite spongy scaffolds for biomedical applications. In TechConnect World Innovation Conference & Expo 2015 (pp. 270-273). TechConnect.

Vancouver

Siddiqi SA, Manzoor F, Azhar U, Jamal A, Tariq M, Anwar MS et al. Preparation and investigation of nano-carbonated hydroxy apatite/polymer composite spongy scaffolds for biomedical applications. In TechConnect World Innovation Conference & Expo 2015. TechConnect. 2015. p. 270-273

Author

Siddiqi, S.A. ; Manzoor, F. ; Azhar, U. ; Jamal, A. ; Tariq, M. ; Anwar, M.S. ; Saleem, M. ; Chaudhry, A.A. ; Rehman, I.U. ; M., Laudon (Editor) ; B., Romanowicz (Editor). / Preparation and investigation of nano-carbonated hydroxy apatite/polymer composite spongy scaffolds for biomedical applications. TechConnect World Innovation Conference & Expo 2015. TechConnect, 2015. pp. 270-273

Bibtex

@inproceedings{05bf5dfbb3e14bb69b746ac3fb9b72cc,
title = "Preparation and investigation of nano-carbonated hydroxy apatite/polymer composite spongy scaffolds for biomedical applications",
abstract = "Spongy scaffolds containing nano-carbonatcd hydroxyapatitc (nCHA), with composition Ca10(P04)6- y(C03)y(0H)2,with y=2,4, were prepared by the Iyophilization method. Different polymers, natural gelatin (G), chitosan (CS) and polyvinyl alcohol (PVA), alone or in combination, were used to make their compositcs with nCHA. All the samples were characterized by (XRD), (SEM), (FT-IR) techniques. P3rticlc size and surface area were determined by BET surfacc area analysis. The nCHA containing scaffolds mediated cytotoxicity (MTT assay) and cell attachment studies (SEM) were carried out on rat bone marrow derived mesenchymal stem cell (MSC). SEM studies revealed varying microstmctures for pore sizes, shapes and pore interconnectivicy. All the scaffolds were found to be highly porous, porosities beyond 70%. It is observed that the scafTold morphology changes significantly for one nCHA-'polymer combination to the other. Furthermore we investigated the biocompatibility of these scaffolds by performing cell viability and cell attachment tests. Our results indicated evident cell attachment on all the materials and also no significant cytotoxicity was observed in cells grown with these materials compared with control. The preparation of spongy scaffolds and their biocompatibility augment their potential use in tissue engineering and biomedical applications. {\textcopyright} 2015 by TechConnect. All rights reserved.",
keywords = "Carbonated hydroxyapatue, Cell attachment, Freeze drying, Lyophilization, Polymer scaffolds, Spongy scaffolds, Biocompatibility, Cell culture, Cells, Cytology, Medical applications, Natural polymers, Phosphate minerals, Polymers, Pore size, Stem cells, Tissue engineering, Cell attachments, Scaffolds (biology)",
author = "S.A. Siddiqi and F. Manzoor and U. Azhar and A. Jamal and M. Tariq and M.S. Anwar and M. Saleem and A.A. Chaudhry and I.U. Rehman and Laudon M. and Romanowicz B.",
year = "2015",
language = "English",
isbn = "9781498747295 ",
pages = "270--273",
booktitle = "TechConnect World Innovation Conference & Expo 2015",
publisher = "TechConnect",

}

RIS

TY - GEN

T1 - Preparation and investigation of nano-carbonated hydroxy apatite/polymer composite spongy scaffolds for biomedical applications

AU - Siddiqi, S.A.

AU - Manzoor, F.

AU - Azhar, U.

AU - Jamal, A.

AU - Tariq, M.

AU - Anwar, M.S.

AU - Saleem, M.

AU - Chaudhry, A.A.

AU - Rehman, I.U.

A2 - M., Laudon

A2 - B., Romanowicz

PY - 2015

Y1 - 2015

N2 - Spongy scaffolds containing nano-carbonatcd hydroxyapatitc (nCHA), with composition Ca10(P04)6- y(C03)y(0H)2,with y=2,4, were prepared by the Iyophilization method. Different polymers, natural gelatin (G), chitosan (CS) and polyvinyl alcohol (PVA), alone or in combination, were used to make their compositcs with nCHA. All the samples were characterized by (XRD), (SEM), (FT-IR) techniques. P3rticlc size and surface area were determined by BET surfacc area analysis. The nCHA containing scaffolds mediated cytotoxicity (MTT assay) and cell attachment studies (SEM) were carried out on rat bone marrow derived mesenchymal stem cell (MSC). SEM studies revealed varying microstmctures for pore sizes, shapes and pore interconnectivicy. All the scaffolds were found to be highly porous, porosities beyond 70%. It is observed that the scafTold morphology changes significantly for one nCHA-'polymer combination to the other. Furthermore we investigated the biocompatibility of these scaffolds by performing cell viability and cell attachment tests. Our results indicated evident cell attachment on all the materials and also no significant cytotoxicity was observed in cells grown with these materials compared with control. The preparation of spongy scaffolds and their biocompatibility augment their potential use in tissue engineering and biomedical applications. © 2015 by TechConnect. All rights reserved.

AB - Spongy scaffolds containing nano-carbonatcd hydroxyapatitc (nCHA), with composition Ca10(P04)6- y(C03)y(0H)2,with y=2,4, were prepared by the Iyophilization method. Different polymers, natural gelatin (G), chitosan (CS) and polyvinyl alcohol (PVA), alone or in combination, were used to make their compositcs with nCHA. All the samples were characterized by (XRD), (SEM), (FT-IR) techniques. P3rticlc size and surface area were determined by BET surfacc area analysis. The nCHA containing scaffolds mediated cytotoxicity (MTT assay) and cell attachment studies (SEM) were carried out on rat bone marrow derived mesenchymal stem cell (MSC). SEM studies revealed varying microstmctures for pore sizes, shapes and pore interconnectivicy. All the scaffolds were found to be highly porous, porosities beyond 70%. It is observed that the scafTold morphology changes significantly for one nCHA-'polymer combination to the other. Furthermore we investigated the biocompatibility of these scaffolds by performing cell viability and cell attachment tests. Our results indicated evident cell attachment on all the materials and also no significant cytotoxicity was observed in cells grown with these materials compared with control. The preparation of spongy scaffolds and their biocompatibility augment their potential use in tissue engineering and biomedical applications. © 2015 by TechConnect. All rights reserved.

KW - Carbonated hydroxyapatue

KW - Cell attachment

KW - Freeze drying

KW - Lyophilization

KW - Polymer scaffolds

KW - Spongy scaffolds

KW - Biocompatibility

KW - Cell culture

KW - Cells

KW - Cytology

KW - Medical applications

KW - Natural polymers

KW - Phosphate minerals

KW - Polymers

KW - Pore size

KW - Stem cells

KW - Tissue engineering

KW - Cell attachments

KW - Scaffolds (biology)

M3 - Conference contribution/Paper

SN - 9781498747295

SP - 270

EP - 273

BT - TechConnect World Innovation Conference & Expo 2015

PB - TechConnect

ER -