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Proctolin in the post-genomic era: new insights and challenges

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Proctolin in the post-genomic era: new insights and challenges. / Isaac, R. Elwyn; Taylor, C. A.; Hamasaka, Yasutaka et al.
In: Invertebrate Neuroscience, Vol. 5, No. 2, 10.2004, p. 51-64.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Isaac, RE, Taylor, CA, Hamasaka, Y, Nässel, DR & Shirras, AD 2004, 'Proctolin in the post-genomic era: new insights and challenges', Invertebrate Neuroscience, vol. 5, no. 2, pp. 51-64. https://doi.org/10.1007/s10158-004-0029-5

APA

Isaac, R. E., Taylor, C. A., Hamasaka, Y., Nässel, D. R., & Shirras, A. D. (2004). Proctolin in the post-genomic era: new insights and challenges. Invertebrate Neuroscience, 5(2), 51-64. https://doi.org/10.1007/s10158-004-0029-5

Vancouver

Isaac RE, Taylor CA, Hamasaka Y, Nässel DR, Shirras AD. Proctolin in the post-genomic era: new insights and challenges. Invertebrate Neuroscience. 2004 Oct;5(2):51-64. doi: 10.1007/s10158-004-0029-5

Author

Isaac, R. Elwyn ; Taylor, C. A. ; Hamasaka, Yasutaka et al. / Proctolin in the post-genomic era : new insights and challenges. In: Invertebrate Neuroscience. 2004 ; Vol. 5, No. 2. pp. 51-64.

Bibtex

@article{13562ce4400b4b76bc6d74ef1a06cd77,
title = "Proctolin in the post-genomic era: new insights and challenges",
abstract = "Complete understanding of how neuropeptides operate as neuromodulators and neurohormones requires integration of knowledge obtained at different levels of biology, including molecular, biochemical, physiological and whole organism studies. Major advances have recently been made in the understanding of the molecular basis of neuropeptide action in invertebrates by analysis of data generated from sequencing the genomes of several insect species, especially that of Drosophila melanogaster. This approach has quickly led to the identification of genes encoding: (1) novel neuropeptide sequences, (2) neuropeptide receptors and (3) peptidases that might be responsible for the processing and inactivation of neuropeptides. In this article, we review our current knowledge of the biosynthesis, receptor interaction and metabolic inactivation of the arthropod neuropeptide, proctolin, and how the analysis and exploitation of genome sequencing projects has provided new insights.",
keywords = "Proctolin, Genomics, G protein-coupled receptor, Aminopeptidase, Dipeptidyl aminopeptidase III",
author = "Isaac, {R. Elwyn} and Taylor, {C. A.} and Yasutaka Hamasaka and N{\"a}ssel, {Dick R.} and Shirras, {Alan D.}",
year = "2004",
month = oct,
doi = "10.1007/s10158-004-0029-5",
language = "English",
volume = "5",
pages = "51--64",
journal = "Invertebrate Neuroscience",
issn = "1354-2516",
publisher = "Springer Verlag",
number = "2",

}

RIS

TY - JOUR

T1 - Proctolin in the post-genomic era

T2 - new insights and challenges

AU - Isaac, R. Elwyn

AU - Taylor, C. A.

AU - Hamasaka, Yasutaka

AU - Nässel, Dick R.

AU - Shirras, Alan D.

PY - 2004/10

Y1 - 2004/10

N2 - Complete understanding of how neuropeptides operate as neuromodulators and neurohormones requires integration of knowledge obtained at different levels of biology, including molecular, biochemical, physiological and whole organism studies. Major advances have recently been made in the understanding of the molecular basis of neuropeptide action in invertebrates by analysis of data generated from sequencing the genomes of several insect species, especially that of Drosophila melanogaster. This approach has quickly led to the identification of genes encoding: (1) novel neuropeptide sequences, (2) neuropeptide receptors and (3) peptidases that might be responsible for the processing and inactivation of neuropeptides. In this article, we review our current knowledge of the biosynthesis, receptor interaction and metabolic inactivation of the arthropod neuropeptide, proctolin, and how the analysis and exploitation of genome sequencing projects has provided new insights.

AB - Complete understanding of how neuropeptides operate as neuromodulators and neurohormones requires integration of knowledge obtained at different levels of biology, including molecular, biochemical, physiological and whole organism studies. Major advances have recently been made in the understanding of the molecular basis of neuropeptide action in invertebrates by analysis of data generated from sequencing the genomes of several insect species, especially that of Drosophila melanogaster. This approach has quickly led to the identification of genes encoding: (1) novel neuropeptide sequences, (2) neuropeptide receptors and (3) peptidases that might be responsible for the processing and inactivation of neuropeptides. In this article, we review our current knowledge of the biosynthesis, receptor interaction and metabolic inactivation of the arthropod neuropeptide, proctolin, and how the analysis and exploitation of genome sequencing projects has provided new insights.

KW - Proctolin

KW - Genomics

KW - G protein-coupled receptor

KW - Aminopeptidase

KW - Dipeptidyl aminopeptidase III

U2 - 10.1007/s10158-004-0029-5

DO - 10.1007/s10158-004-0029-5

M3 - Journal article

VL - 5

SP - 51

EP - 64

JO - Invertebrate Neuroscience

JF - Invertebrate Neuroscience

SN - 1354-2516

IS - 2

ER -