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Rapid increase in Omicron infections in England during December 2021: REACT-1 study

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Rapid increase in Omicron infections in England during December 2021: REACT-1 study. / Elliott, Paul; Bodinier, Barbara; Eales, Oliver et al.
In: Science, Vol. 375, No. 6587, eabn8347, 28.02.2022, p. 1406-1411.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Elliott, P, Bodinier, B, Eales, O, Wang, H, Haw, D, Elliott, J, Whitaker, M, Jonnerby, J, Tang, D, Walters, CE, Atchison, C, Diggle, PJ, Page, AJ, Trotter, AJ, Ashby, D, Barclay, W, Taylor, G, Ward, H, Darzi, A, Cooke, GS, Chadeau-Hyam, M & Donnelly, CA 2022, 'Rapid increase in Omicron infections in England during December 2021: REACT-1 study', Science, vol. 375, no. 6587, eabn8347, pp. 1406-1411. https://doi.org/10.1126/science.abn8347

APA

Elliott, P., Bodinier, B., Eales, O., Wang, H., Haw, D., Elliott, J., Whitaker, M., Jonnerby, J., Tang, D., Walters, C. E., Atchison, C., Diggle, P. J., Page, A. J., Trotter, A. J., Ashby, D., Barclay, W., Taylor, G., Ward, H., Darzi, A., ... Donnelly, C. A. (2022). Rapid increase in Omicron infections in England during December 2021: REACT-1 study. Science, 375(6587), 1406-1411. Article eabn8347. https://doi.org/10.1126/science.abn8347

Vancouver

Elliott P, Bodinier B, Eales O, Wang H, Haw D, Elliott J et al. Rapid increase in Omicron infections in England during December 2021: REACT-1 study. Science. 2022 Feb 28;375(6587):1406-1411. eabn8347. Epub 2022 Feb 8. doi: 10.1126/science.abn8347

Author

Elliott, Paul ; Bodinier, Barbara ; Eales, Oliver et al. / Rapid increase in Omicron infections in England during December 2021 : REACT-1 study. In: Science. 2022 ; Vol. 375, No. 6587. pp. 1406-1411.

Bibtex

@article{33c825381e834cb692b77a09c6a66f25,
title = "Rapid increase in Omicron infections in England during December 2021: REACT-1 study",
abstract = "The unprecedented rise in SARS-CoV-2 infections during December 2021 was concurrent with rapid spread of the Omicron variant in England and globally. We analyzed prevalence of SARS-CoV-2 and its dynamics in England from end November to mid-December 2021 among almost 100,000 participants from the REACT-1 study. Prevalence was high with rapid growth nationally and particularly in London during December 2021, and an increasing proportion of infections due to Omicron. We observed large falls in swab positivity among mostly vaccinated older children (12-17 years) compared with unvaccinated younger children (5-11 years), and in adults who received a third (booster) vaccine dose vs. two doses. Our results reinforce the importance of vaccination and booster campaigns, although additional measures have been needed to control the rapid growth of the Omicron variant.",
author = "Paul Elliott and Barbara Bodinier and Oliver Eales and Haowei Wang and David Haw and Joshua Elliott and Matthew Whitaker and Jakob Jonnerby and David Tang and Walters, {Caroline E} and Christina Atchison and Diggle, {Peter J} and Page, {Andrew J} and Trotter, {Alexander J} and Deborah Ashby and Wendy Barclay and Graham Taylor and Helen Ward and Ara Darzi and Cooke, {Graham S} and Marc Chadeau-Hyam and Donnelly, {Christl A}",
year = "2022",
month = feb,
day = "28",
doi = "10.1126/science.abn8347",
language = "English",
volume = "375",
pages = "1406--1411",
journal = "Science",
issn = "1095-9203",
publisher = "American Association for the Advancement of Science",
number = "6587",

}

RIS

TY - JOUR

T1 - Rapid increase in Omicron infections in England during December 2021

T2 - REACT-1 study

AU - Elliott, Paul

AU - Bodinier, Barbara

AU - Eales, Oliver

AU - Wang, Haowei

AU - Haw, David

AU - Elliott, Joshua

AU - Whitaker, Matthew

AU - Jonnerby, Jakob

AU - Tang, David

AU - Walters, Caroline E

AU - Atchison, Christina

AU - Diggle, Peter J

AU - Page, Andrew J

AU - Trotter, Alexander J

AU - Ashby, Deborah

AU - Barclay, Wendy

AU - Taylor, Graham

AU - Ward, Helen

AU - Darzi, Ara

AU - Cooke, Graham S

AU - Chadeau-Hyam, Marc

AU - Donnelly, Christl A

PY - 2022/2/28

Y1 - 2022/2/28

N2 - The unprecedented rise in SARS-CoV-2 infections during December 2021 was concurrent with rapid spread of the Omicron variant in England and globally. We analyzed prevalence of SARS-CoV-2 and its dynamics in England from end November to mid-December 2021 among almost 100,000 participants from the REACT-1 study. Prevalence was high with rapid growth nationally and particularly in London during December 2021, and an increasing proportion of infections due to Omicron. We observed large falls in swab positivity among mostly vaccinated older children (12-17 years) compared with unvaccinated younger children (5-11 years), and in adults who received a third (booster) vaccine dose vs. two doses. Our results reinforce the importance of vaccination and booster campaigns, although additional measures have been needed to control the rapid growth of the Omicron variant.

AB - The unprecedented rise in SARS-CoV-2 infections during December 2021 was concurrent with rapid spread of the Omicron variant in England and globally. We analyzed prevalence of SARS-CoV-2 and its dynamics in England from end November to mid-December 2021 among almost 100,000 participants from the REACT-1 study. Prevalence was high with rapid growth nationally and particularly in London during December 2021, and an increasing proportion of infections due to Omicron. We observed large falls in swab positivity among mostly vaccinated older children (12-17 years) compared with unvaccinated younger children (5-11 years), and in adults who received a third (booster) vaccine dose vs. two doses. Our results reinforce the importance of vaccination and booster campaigns, although additional measures have been needed to control the rapid growth of the Omicron variant.

U2 - 10.1126/science.abn8347

DO - 10.1126/science.abn8347

M3 - Journal article

C2 - 35133177

VL - 375

SP - 1406

EP - 1411

JO - Science

JF - Science

SN - 1095-9203

IS - 6587

M1 - eabn8347

ER -