Final published version
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Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Rapid spread of a densovirus in a major crop pest following wide-scale adoption of bt-cotton in china
AU - Xiao, Y.
AU - Li, W.
AU - Yang, X.
AU - Xu, P.
AU - Jin, M.
AU - Yuan, H.
AU - Zheng, W.
AU - Soberón, M.
AU - Bravo, A.
AU - Wilson, K.
AU - Wu, K.
PY - 2021/7/15
Y1 - 2021/7/15
N2 - Bacillus thuringiensis (Bt) crops have been widely planted and the effects of Bt-crops on populations of the target and non-target insect pests have been well studied. However, the effects of Bt-crops exposure on microorganisms that interact with crop pests have not previously been quantified. Here, we use laboratory and field data to show that infection of Helicoverpa armigera with a densovirus (HaDV2) is associated with its enhanced growth and tolerance to Bt-cotton. Moreover, field monitoring showed a much higher incidence of cotton bollworm infection with HaDV2 in regions cultivated with Bt-cotton than in regions without it, with the rate of densovirus infection increasing with increasing use of Bt-cotton. RNA-seq suggested tolerance to both baculovirus and Cry1Ac were enhanced via the immune-related pathways. These findings suggest that exposure to Bt-crops has selected for beneficial interactions between the target pest and a mutualistic microorganism that enhances its performance on Bt-crops under field conditions. © Xiao et al.
AB - Bacillus thuringiensis (Bt) crops have been widely planted and the effects of Bt-crops on populations of the target and non-target insect pests have been well studied. However, the effects of Bt-crops exposure on microorganisms that interact with crop pests have not previously been quantified. Here, we use laboratory and field data to show that infection of Helicoverpa armigera with a densovirus (HaDV2) is associated with its enhanced growth and tolerance to Bt-cotton. Moreover, field monitoring showed a much higher incidence of cotton bollworm infection with HaDV2 in regions cultivated with Bt-cotton than in regions without it, with the rate of densovirus infection increasing with increasing use of Bt-cotton. RNA-seq suggested tolerance to both baculovirus and Cry1Ac were enhanced via the immune-related pathways. These findings suggest that exposure to Bt-crops has selected for beneficial interactions between the target pest and a mutualistic microorganism that enhances its performance on Bt-crops under field conditions. © Xiao et al.
KW - adoption
KW - article
KW - Bacillus thuringiensis
KW - bacterium culture
KW - Baculoviridae
KW - China
KW - controlled study
KW - crop pest
KW - Densovirinae
KW - field study
KW - Helicoverpa armigera
KW - human cell
KW - immune-related gene
KW - incidence
KW - microorganism
KW - nonhuman
KW - RNA sequencing
KW - target pest
U2 - 10.7554/eLife.66913
DO - 10.7554/eLife.66913
M3 - Journal article
VL - 10
JO - eLife
JF - eLife
SN - 2050-084X
M1 - e66913
ER -