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George, AJT, Titus, JA, Jost, CR, Kurucz, I, Perez, P, Andrew, SM, Nicholls, PJ, Huston, JS & Segal, DM 1995, '
Redirection of cellular cytotoxicity: a two step approach using recombinant single-chain Fv molecules.',
Cell Biochemistry and Biophysics, vol. 26, no. 3, pp. 153-165.
https://doi.org/10.1007/BF02791577APA
George, A. J. T., Titus, J. A., Jost, C. R., Kurucz, I., Perez, P., Andrew, S. M., Nicholls, P. J., Huston, J. S., & Segal, D. M. (1995).
Redirection of cellular cytotoxicity: a two step approach using recombinant single-chain Fv molecules. Cell Biochemistry and Biophysics,
26(3), 153-165.
https://doi.org/10.1007/BF02791577Vancouver
Author
Bibtex
@article{250cadcfd1e54468b59415aff189c824,
title = "Redirection of cellular cytotoxicity: a two step approach using recombinant single-chain Fv molecules.",
abstract = "In this article the authors discuss an indirect system for redirecting cellular cytotoxicity, which utilizes a “universal” bispecific antibody to redirect T-cells to kill cells targeted with single-chain Fv (sFv) fusion proteins that carry a peptide tag recognized by the bispecific antibody. This approach has a number of theoretical advantages in the immunotherapy of cancer.",
keywords = "Bispecific antibody - single-chain Fv - redirected cellular cytotoxicity - immunotherapy",
author = "George, {A. J. T.} and Titus, {J. A.} and Jost, {C. R.} and I. Kurucz and P. Perez and Andrew, {S. M.} and Nicholls, {P. J.} and Huston, {J. S.} and Segal, {D. M.}",
year = "1995",
month = jun,
doi = "10.1007/BF02791577",
language = "English",
volume = "26",
pages = "153--165",
journal = "Cell Biochemistry and Biophysics",
issn = "1085-9195",
publisher = "Humana Press",
number = "3",
}
RIS
TY - JOUR
T1 - Redirection of cellular cytotoxicity: a two step approach using recombinant single-chain Fv molecules.
AU - George, A. J. T.
AU - Titus, J. A.
AU - Jost, C. R.
AU - Kurucz, I.
AU - Perez, P.
AU - Andrew, S. M.
AU - Nicholls, P. J.
AU - Huston, J. S.
AU - Segal, D. M.
PY - 1995/6
Y1 - 1995/6
N2 - In this article the authors discuss an indirect system for redirecting cellular cytotoxicity, which utilizes a “universal” bispecific antibody to redirect T-cells to kill cells targeted with single-chain Fv (sFv) fusion proteins that carry a peptide tag recognized by the bispecific antibody. This approach has a number of theoretical advantages in the immunotherapy of cancer.
AB - In this article the authors discuss an indirect system for redirecting cellular cytotoxicity, which utilizes a “universal” bispecific antibody to redirect T-cells to kill cells targeted with single-chain Fv (sFv) fusion proteins that carry a peptide tag recognized by the bispecific antibody. This approach has a number of theoretical advantages in the immunotherapy of cancer.
KW - Bispecific antibody - single-chain Fv - redirected cellular cytotoxicity - immunotherapy
U2 - 10.1007/BF02791577
DO - 10.1007/BF02791577
M3 - Journal article
VL - 26
SP - 153
EP - 165
JO - Cell Biochemistry and Biophysics
JF - Cell Biochemistry and Biophysics
SN - 1085-9195
IS - 3
ER -
