Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Regions responsible for organizing the microtubular cytoskeletons of extra-embryonic membranes
AU - Hooper, P
AU - Byrne, S
AU - Ockleford, C
PY - 2001
Y1 - 2001
N2 - We have identified putative microtubule-organising centres in whole mounts and frozen sections of full term human placenta, amniochorion and first trimester chorionic villus tissue by indirect immunofluorescence confocal laser scanning microscopy. These sites may perform a crucial executive role in the morphogenesis of human extra-embryonic membranes, and also may establish polarity in the amniotic epithelium and mediate the branching pattern of growth essential to the production of the chorionic villus tree.
AB - We have identified putative microtubule-organising centres in whole mounts and frozen sections of full term human placenta, amniochorion and first trimester chorionic villus tissue by indirect immunofluorescence confocal laser scanning microscopy. These sites may perform a crucial executive role in the morphogenesis of human extra-embryonic membranes, and also may establish polarity in the amniotic epithelium and mediate the branching pattern of growth essential to the production of the chorionic villus tree.
KW - Amnion
KW - Antigens
KW - Chorion
KW - Chorionic Villi
KW - Cytoskeleton
KW - Female
KW - Fluorescent Antibody Technique
KW - Gestational Age
KW - Humans
KW - Microtubules
KW - Placenta
KW - Pregnancy
KW - Tubulin
M3 - Journal article
C2 - 11732594
VL - 106
SP - 331
EP - 338
JO - Italian Journal of Anatomy and Embryology
JF - Italian Journal of Anatomy and Embryology
SN - 1122-6714
IS - 2 Suppl 2
ER -