Final published version
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Research output: Contribution to Journal/Magazine › Review article › peer-review
Research output: Contribution to Journal/Magazine › Review article › peer-review
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TY - JOUR
T1 - Research progress on peptides that inhibit melanin synthesis
AU - Yu, Binrui
AU - Wang, Nailong
AU - Cai, Shanshan
AU - Yan, Hao
AU - Sun, Shaojia
AU - Wang, Siru
AU - Li, Ye
AU - Liang, Zhengting
PY - 2025/7/2
Y1 - 2025/7/2
N2 - Melanin produced by melanocytes, primarily determines human skin color and protects against ultraviolet radiation. However, excessive melanin deposition can lead to skin conditions such as freckles, age spots, and moles, potentially causing aesthetic concerns and psychological distress. Consequently, there is significant research interest in developing safe and effective whitening products that inhibit melanin synthesis. Bioactive peptides represent a promising compound category that effectively reduces melanin synthesis with minimal side effects. This review explores melanin pigmentation, identifies sources of peptides that inhibit melanin synthesis, and elucidates the mechanisms by which these peptides operate, aiming to contribute to developing novel whitening products.
AB - Melanin produced by melanocytes, primarily determines human skin color and protects against ultraviolet radiation. However, excessive melanin deposition can lead to skin conditions such as freckles, age spots, and moles, potentially causing aesthetic concerns and psychological distress. Consequently, there is significant research interest in developing safe and effective whitening products that inhibit melanin synthesis. Bioactive peptides represent a promising compound category that effectively reduces melanin synthesis with minimal side effects. This review explores melanin pigmentation, identifies sources of peptides that inhibit melanin synthesis, and elucidates the mechanisms by which these peptides operate, aiming to contribute to developing novel whitening products.
KW - bioactive peptides
KW - excessive deposition
KW - inhibition
KW - tyrosinase
KW - whitening
KW - melanin
U2 - 10.3389/fphar.2025.1610623
DO - 10.3389/fphar.2025.1610623
M3 - Review article
C2 - 40672371
VL - 16
JO - Frontiers in Pharmacology
JF - Frontiers in Pharmacology
SN - 1663-9812
M1 - 1610623
ER -