Final published version
Licence: CC BY: Creative Commons Attribution 4.0 International License
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Resurgence of SARS-CoV-2: Detection by community viral surveillance
AU - Riley, S.
AU - Ainslie, K.E.C.
AU - Eales, O.
AU - Walters, C.E.
AU - Wang, H.
AU - Atchison, C.
AU - Fronterre, C.
AU - Diggle, P.J.
AU - Ashby, D.
AU - Donnelly, C.A.
AU - Cooke, G.
AU - Barclay, W.
AU - Ward, H.
AU - Darzi, A.
AU - Elliott, P.
PY - 2021/5/28
Y1 - 2021/5/28
N2 - Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in England based on self-administered swab results from ~594,000 individuals tested for SARS-CoV-2, regardless of symptoms, between May and the beginning of September 2020. The epidemic declined between May and July 2020 but then increased gradually from mid-August, accelerating into early September 2020 at the start of the second wave. When compared with cases detected through routine surveillance, we report here a longer period of decline and a younger age distribution. Representative community sampling for SARS-CoV-2 can substantially improve situational awareness and feed into the public health response even at low prevalence.
AB - Surveillance of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has mainly relied on case reporting, which is biased by health service performance, test availability, and test-seeking behaviors. We report a community-wide national representative surveillance program in England based on self-administered swab results from ~594,000 individuals tested for SARS-CoV-2, regardless of symptoms, between May and the beginning of September 2020. The epidemic declined between May and July 2020 but then increased gradually from mid-August, accelerating into early September 2020 at the start of the second wave. When compared with cases detected through routine surveillance, we report here a longer period of decline and a younger age distribution. Representative community sampling for SARS-CoV-2 can substantially improve situational awareness and feed into the public health response even at low prevalence.
KW - disease severity
KW - epidemic
KW - health services
KW - public health
KW - severe acute respiratory syndrome
KW - England
KW - United Kingdom
KW - SARS coronavirus
U2 - 10.1126/science.abf0874
DO - 10.1126/science.abf0874
M3 - Journal article
VL - 372
SP - 990
EP - 995
JO - Science
JF - Science
SN - 0036-8075
IS - 6545
ER -