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Review of U.S. EPA's ORD Staff Handbook for Developing IRIS Assessments

Research output: Book/Report/ProceedingsCommissioned report

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Review of U.S. EPA's ORD Staff Handbook for Developing IRIS Assessments. / NASEM.
National Academy of Sciences, 2021. 120 p.

Research output: Book/Report/ProceedingsCommissioned report

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NASEM. Review of U.S. EPA's ORD Staff Handbook for Developing IRIS Assessments. National Academy of Sciences, 2021. 120 p. doi: 10.17226/26289

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NASEM. / Review of U.S. EPA's ORD Staff Handbook for Developing IRIS Assessments. National Academy of Sciences, 2021. 120 p.

Bibtex

@book{e220f78525384797851dfdf9f5848561,
title = "Review of U.S. EPA's ORD Staff Handbook for Developing IRIS Assessments",
abstract = "The U.S. Environmental Protection Agency's (EPA) Integrated Risk Information System (IRIS) program develops human health assessments that focus on hazard identification and dose-response analyses for chemicals in the environment. The ORD Staff Handbook for Developing IRIS Assessments (the handbook) provides guidance to scientists who perform the IRIS assessments in order to foster consistency in the assessments and enhance transparency about the IRIS assessment process. At the request of the EPA, this report reviews the procedures and considerations for operationalizing the principles of systematic reviews and the methods described in the handbook for determining the scope of the IRIS assessments, evidence integration, extrapolation techniques, dose-response analyses, and characterization of uncertainties.",
keywords = "Systematic Review, chemical risk assessment",
author = "NASEM and Paul Whaley",
year = "2021",
month = nov,
day = "30",
doi = "10.17226/26289",
language = "English",
publisher = "National Academy of Sciences",

}

RIS

TY - BOOK

T1 - Review of U.S. EPA's ORD Staff Handbook for Developing IRIS Assessments

AU - NASEM

AU - Whaley, Paul

PY - 2021/11/30

Y1 - 2021/11/30

N2 - The U.S. Environmental Protection Agency's (EPA) Integrated Risk Information System (IRIS) program develops human health assessments that focus on hazard identification and dose-response analyses for chemicals in the environment. The ORD Staff Handbook for Developing IRIS Assessments (the handbook) provides guidance to scientists who perform the IRIS assessments in order to foster consistency in the assessments and enhance transparency about the IRIS assessment process. At the request of the EPA, this report reviews the procedures and considerations for operationalizing the principles of systematic reviews and the methods described in the handbook for determining the scope of the IRIS assessments, evidence integration, extrapolation techniques, dose-response analyses, and characterization of uncertainties.

AB - The U.S. Environmental Protection Agency's (EPA) Integrated Risk Information System (IRIS) program develops human health assessments that focus on hazard identification and dose-response analyses for chemicals in the environment. The ORD Staff Handbook for Developing IRIS Assessments (the handbook) provides guidance to scientists who perform the IRIS assessments in order to foster consistency in the assessments and enhance transparency about the IRIS assessment process. At the request of the EPA, this report reviews the procedures and considerations for operationalizing the principles of systematic reviews and the methods described in the handbook for determining the scope of the IRIS assessments, evidence integration, extrapolation techniques, dose-response analyses, and characterization of uncertainties.

KW - Systematic Review

KW - chemical risk assessment

U2 - 10.17226/26289

DO - 10.17226/26289

M3 - Commissioned report

BT - Review of U.S. EPA's ORD Staff Handbook for Developing IRIS Assessments

PB - National Academy of Sciences

ER -