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Screening and diagnosing dementia in people with Down’s syndrome: implications of using the DLD questionnaire

Research output: Contribution to Journal/MagazineJournal articlepeer-review

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Screening and diagnosing dementia in people with Down’s syndrome: implications of using the DLD questionnaire. / Perera, Bhathika; Kamieniarz, Lukasz; Iftikhar, Mashal et al.
In: Advances in Mental Health and Intellectual Disabilities, Vol. 16, No. 4, 24.10.2022, p. 239-248.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Perera, B, Kamieniarz, L, Iftikhar, M & Solomou, S 2022, 'Screening and diagnosing dementia in people with Down’s syndrome: implications of using the DLD questionnaire', Advances in Mental Health and Intellectual Disabilities, vol. 16, no. 4, pp. 239-248. https://doi.org/10.1108/amhid-04-2022-0015

APA

Perera, B., Kamieniarz, L., Iftikhar, M., & Solomou, S. (2022). Screening and diagnosing dementia in people with Down’s syndrome: implications of using the DLD questionnaire. Advances in Mental Health and Intellectual Disabilities, 16(4), 239-248. https://doi.org/10.1108/amhid-04-2022-0015

Vancouver

Perera B, Kamieniarz L, Iftikhar M, Solomou S. Screening and diagnosing dementia in people with Down’s syndrome: implications of using the DLD questionnaire. Advances in Mental Health and Intellectual Disabilities. 2022 Oct 24;16(4):239-248. Epub 2022 Oct 11. doi: 10.1108/amhid-04-2022-0015

Author

Perera, Bhathika ; Kamieniarz, Lukasz ; Iftikhar, Mashal et al. / Screening and diagnosing dementia in people with Down’s syndrome : implications of using the DLD questionnaire. In: Advances in Mental Health and Intellectual Disabilities. 2022 ; Vol. 16, No. 4. pp. 239-248.

Bibtex

@article{b8b83d4d091046dba76f1f880c2e27af,
title = "Screening and diagnosing dementia in people with Down{\textquoteright}s syndrome: implications of using the DLD questionnaire",
abstract = "Purpose The Dementia Questionnaire for People with Learning Disabilities (DLD) is one of the main screening and monitoring tools for dementia in people with Down{\textquoteright}s syndrome (DS). As part of a quality improvement project to improve the care for people with DS and dementia in an intellectual disability service, the authors studied the screening and monitoring process by retrospectively investigating the use of DLD and exploring clinicians{\textquoteright} experience of using it. Design/methodology/approach DLDs completed in the service was retrospectively assessed. Changes in DLD scores were matched against people who received a clinical diagnosis of dementia. Data were analysed to estimate sensitivity, specificity and predictive values of DLD. A questionnaire was used to assess clinicians{\textquoteright} experience. Findings Data for 20 service users was collected. DLD cognitive scores showed 80% sensitivity and 60% specificity for the diagnosis of dementia, with a positive predictive value of 40% and negative predictive value of 90%. Staff found DLD to be easy to perform but time consuming. This led to the preparation of a decision tool for appropriateness of performing a DLD. Originality/value The results show that a negative DLD helps to exclude dementia where there is concern over cognitive decline, but a positive result is not specific enough to suggest the possibility of dementia. This shows that DLD may have limitations if used as a screening tool alone but could be used for the monitoring of the disease trajectory of those with a confirmed diagnosis as well as to establish a baseline DLD when a person is screened for dementia first.",
keywords = "Down's syndrome, Memory, Quality improvement, Dementia, Intellectual disability, Dementia questionnaire for people with learning disabilities",
author = "Bhathika Perera and Lukasz Kamieniarz and Mashal Iftikhar and Solomis Solomou",
note = "This article is (c) Emerald Group Publishing and permission has been granted for this version to appear here. Emerald does not grant permission for this article to be further copied/distributed or hosted elsewhere without the express permission from Emerald Group Publishing Limited. ",
year = "2022",
month = oct,
day = "24",
doi = "10.1108/amhid-04-2022-0015",
language = "English",
volume = "16",
pages = "239--248",
journal = "Advances in Mental Health and Intellectual Disabilities",
issn = "2044-1282",
publisher = "Emerald Group Publishing Ltd.",
number = "4",

}

RIS

TY - JOUR

T1 - Screening and diagnosing dementia in people with Down’s syndrome

T2 - implications of using the DLD questionnaire

AU - Perera, Bhathika

AU - Kamieniarz, Lukasz

AU - Iftikhar, Mashal

AU - Solomou, Solomis

N1 - This article is (c) Emerald Group Publishing and permission has been granted for this version to appear here. Emerald does not grant permission for this article to be further copied/distributed or hosted elsewhere without the express permission from Emerald Group Publishing Limited.

PY - 2022/10/24

Y1 - 2022/10/24

N2 - Purpose The Dementia Questionnaire for People with Learning Disabilities (DLD) is one of the main screening and monitoring tools for dementia in people with Down’s syndrome (DS). As part of a quality improvement project to improve the care for people with DS and dementia in an intellectual disability service, the authors studied the screening and monitoring process by retrospectively investigating the use of DLD and exploring clinicians’ experience of using it. Design/methodology/approach DLDs completed in the service was retrospectively assessed. Changes in DLD scores were matched against people who received a clinical diagnosis of dementia. Data were analysed to estimate sensitivity, specificity and predictive values of DLD. A questionnaire was used to assess clinicians’ experience. Findings Data for 20 service users was collected. DLD cognitive scores showed 80% sensitivity and 60% specificity for the diagnosis of dementia, with a positive predictive value of 40% and negative predictive value of 90%. Staff found DLD to be easy to perform but time consuming. This led to the preparation of a decision tool for appropriateness of performing a DLD. Originality/value The results show that a negative DLD helps to exclude dementia where there is concern over cognitive decline, but a positive result is not specific enough to suggest the possibility of dementia. This shows that DLD may have limitations if used as a screening tool alone but could be used for the monitoring of the disease trajectory of those with a confirmed diagnosis as well as to establish a baseline DLD when a person is screened for dementia first.

AB - Purpose The Dementia Questionnaire for People with Learning Disabilities (DLD) is one of the main screening and monitoring tools for dementia in people with Down’s syndrome (DS). As part of a quality improvement project to improve the care for people with DS and dementia in an intellectual disability service, the authors studied the screening and monitoring process by retrospectively investigating the use of DLD and exploring clinicians’ experience of using it. Design/methodology/approach DLDs completed in the service was retrospectively assessed. Changes in DLD scores were matched against people who received a clinical diagnosis of dementia. Data were analysed to estimate sensitivity, specificity and predictive values of DLD. A questionnaire was used to assess clinicians’ experience. Findings Data for 20 service users was collected. DLD cognitive scores showed 80% sensitivity and 60% specificity for the diagnosis of dementia, with a positive predictive value of 40% and negative predictive value of 90%. Staff found DLD to be easy to perform but time consuming. This led to the preparation of a decision tool for appropriateness of performing a DLD. Originality/value The results show that a negative DLD helps to exclude dementia where there is concern over cognitive decline, but a positive result is not specific enough to suggest the possibility of dementia. This shows that DLD may have limitations if used as a screening tool alone but could be used for the monitoring of the disease trajectory of those with a confirmed diagnosis as well as to establish a baseline DLD when a person is screened for dementia first.

KW - Down's syndrome

KW - Memory

KW - Quality improvement

KW - Dementia

KW - Intellectual disability

KW - Dementia questionnaire for people with learning disabilities

U2 - 10.1108/amhid-04-2022-0015

DO - 10.1108/amhid-04-2022-0015

M3 - Journal article

VL - 16

SP - 239

EP - 248

JO - Advances in Mental Health and Intellectual Disabilities

JF - Advances in Mental Health and Intellectual Disabilities

SN - 2044-1282

IS - 4

ER -