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Setting Our Sights on Infectious Diseases

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Setting Our Sights on Infectious Diseases. / De Rycker, M.; Horn, D.; Aldridge, B. et al.
In: ACS Infectious Diseases, Vol. 6, No. 1, 10.01.2020, p. 3-13.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

De Rycker, M, Horn, D, Aldridge, B, Amewu, RK, Barry, CE, Buckner, FS, Cook, S, Ferguson, MAJ, Gobeau, N, Herrmann, J, Herrling, P, Hope, W, Keiser, J, Lafuente-Monasterio, MJ, Leeson, PD, Leroy, D, Manjunatha, UH, McCarthy, J, Miles, TJ, Mizrahi, V, Moshynets, O, Niles, J, Overington, JP, Pottage, J, Rao, SPS, Read, KD, Ribeiro, I, Silver, LL, Southern, J, Spangenberg, T, Sundar, S, Taylor, C, Van Voorhis, W, White, NJ, Wyllie, S, Wyatt, PG & Gilbert, IH 2020, 'Setting Our Sights on Infectious Diseases', ACS Infectious Diseases, vol. 6, no. 1, pp. 3-13. https://doi.org/10.1021/acsinfecdis.9b00371

APA

De Rycker, M., Horn, D., Aldridge, B., Amewu, R. K., Barry, C. E., Buckner, F. S., Cook, S., Ferguson, M. A. J., Gobeau, N., Herrmann, J., Herrling, P., Hope, W., Keiser, J., Lafuente-Monasterio, M. J., Leeson, P. D., Leroy, D., Manjunatha, U. H., McCarthy, J., Miles, T. J., ... Gilbert, I. H. (2020). Setting Our Sights on Infectious Diseases. ACS Infectious Diseases, 6(1), 3-13. https://doi.org/10.1021/acsinfecdis.9b00371

Vancouver

De Rycker M, Horn D, Aldridge B, Amewu RK, Barry CE, Buckner FS et al. Setting Our Sights on Infectious Diseases. ACS Infectious Diseases. 2020 Jan 10;6(1):3-13. Epub 2019 Dec 6. doi: 10.1021/acsinfecdis.9b00371

Author

De Rycker, M. ; Horn, D. ; Aldridge, B. et al. / Setting Our Sights on Infectious Diseases. In: ACS Infectious Diseases. 2020 ; Vol. 6, No. 1. pp. 3-13.

Bibtex

@article{7864fb1b6fc84bb18b0ecf9611ac3216,
title = "Setting Our Sights on Infectious Diseases",
abstract = "In May 2019, the Wellcome Centre for Anti-Infectives Research (WCAIR) at the University of Dundee, UK, held an international conference with the aim of discussing some key questions around discovering new medicines for infectious diseases and a particular focus on diseases affecting Low and Middle Income Countries. There is an urgent need for new drugs to treat most infectious diseases. We were keen to see if there were lessons that we could learn across different disease areas and between the preclinical and clinical phases with the aim of exploring how we can improve and speed up the drug discovery, translational, and clinical development processes. We started with an introductory session on the current situation and then worked backward from clinical development to combination therapy, pharmacokinetic/pharmacodynamic (PK/PD) studies, drug discovery pathways, and new starting points and targets. This Viewpoint aims to capture some of the learnings.",
author = "{De Rycker}, M. and D. Horn and B. Aldridge and R.K. Amewu and C.E. Barry and F.S. Buckner and S. Cook and M.A.J. Ferguson and N. Gobeau and J. Herrmann and P. Herrling and W. Hope and J. Keiser and M.J. Lafuente-Monasterio and P.D. Leeson and D. Leroy and U.H. Manjunatha and J. McCarthy and T.J. Miles and V. Mizrahi and O. Moshynets and J. Niles and J.P. Overington and J. Pottage and S.P.S. Rao and K.D. Read and I. Ribeiro and L.L. Silver and J. Southern and T. Spangenberg and S. Sundar and C. Taylor and {Van Voorhis}, W. and N.J. White and S. Wyllie and P.G. Wyatt and I.H. Gilbert",
year = "2020",
month = jan,
day = "10",
doi = "10.1021/acsinfecdis.9b00371",
language = "English",
volume = "6",
pages = "3--13",
journal = "ACS Infectious Diseases",
publisher = "American Chemical Society",
number = "1",

}

RIS

TY - JOUR

T1 - Setting Our Sights on Infectious Diseases

AU - De Rycker, M.

AU - Horn, D.

AU - Aldridge, B.

AU - Amewu, R.K.

AU - Barry, C.E.

AU - Buckner, F.S.

AU - Cook, S.

AU - Ferguson, M.A.J.

AU - Gobeau, N.

AU - Herrmann, J.

AU - Herrling, P.

AU - Hope, W.

AU - Keiser, J.

AU - Lafuente-Monasterio, M.J.

AU - Leeson, P.D.

AU - Leroy, D.

AU - Manjunatha, U.H.

AU - McCarthy, J.

AU - Miles, T.J.

AU - Mizrahi, V.

AU - Moshynets, O.

AU - Niles, J.

AU - Overington, J.P.

AU - Pottage, J.

AU - Rao, S.P.S.

AU - Read, K.D.

AU - Ribeiro, I.

AU - Silver, L.L.

AU - Southern, J.

AU - Spangenberg, T.

AU - Sundar, S.

AU - Taylor, C.

AU - Van Voorhis, W.

AU - White, N.J.

AU - Wyllie, S.

AU - Wyatt, P.G.

AU - Gilbert, I.H.

PY - 2020/1/10

Y1 - 2020/1/10

N2 - In May 2019, the Wellcome Centre for Anti-Infectives Research (WCAIR) at the University of Dundee, UK, held an international conference with the aim of discussing some key questions around discovering new medicines for infectious diseases and a particular focus on diseases affecting Low and Middle Income Countries. There is an urgent need for new drugs to treat most infectious diseases. We were keen to see if there were lessons that we could learn across different disease areas and between the preclinical and clinical phases with the aim of exploring how we can improve and speed up the drug discovery, translational, and clinical development processes. We started with an introductory session on the current situation and then worked backward from clinical development to combination therapy, pharmacokinetic/pharmacodynamic (PK/PD) studies, drug discovery pathways, and new starting points and targets. This Viewpoint aims to capture some of the learnings.

AB - In May 2019, the Wellcome Centre for Anti-Infectives Research (WCAIR) at the University of Dundee, UK, held an international conference with the aim of discussing some key questions around discovering new medicines for infectious diseases and a particular focus on diseases affecting Low and Middle Income Countries. There is an urgent need for new drugs to treat most infectious diseases. We were keen to see if there were lessons that we could learn across different disease areas and between the preclinical and clinical phases with the aim of exploring how we can improve and speed up the drug discovery, translational, and clinical development processes. We started with an introductory session on the current situation and then worked backward from clinical development to combination therapy, pharmacokinetic/pharmacodynamic (PK/PD) studies, drug discovery pathways, and new starting points and targets. This Viewpoint aims to capture some of the learnings.

U2 - 10.1021/acsinfecdis.9b00371

DO - 10.1021/acsinfecdis.9b00371

M3 - Journal article

VL - 6

SP - 3

EP - 13

JO - ACS Infectious Diseases

JF - ACS Infectious Diseases

IS - 1

ER -