TY - JOUR

T1 - Sex/gender differences in individual and joint trajectories of common mental health symptoms in early to middle adolescence

AU - Murray, Aja Louise

AU - Ushakova, Anastasia

AU - Speyer, Lydia

AU - Brown, Ruth

AU - Auyeung, Bonnie

AU - Zhu, Xinxin

PY - 2022/3/31

Y1 - 2022/3/31

N2 - BackgroundEarly to middle adolescence is a critical period of development for mental health issues. Illuminating sex/gender differences in mental health trajectories in this period is important for targeting screening and preventive interventions; however, evidence to date on the extent and nature of sex/gender differences in common mental health issue trajectories in this period has produced mixed findings. There is a particular gap in our knowledge of sex/gender differences in the joint trajectories of commonly co-occurring mental health issues in adolescence, given the strong tendency for mental health issues to co-occur.MethodWe applied sex/gender-stratified latent class growth analysis to an age-heterogeneous cohort (age 10–15) derived from the population-representative UK Household Longitudinal Study. We explored sex/gender differences in attention deficit hyperactivity disorder (ADHD) symptoms, internalizing problems, and conduct problems individually and jointly.ResultsWe found indications of sex/gender differences in a number of areas. There were fewer classes in the optimal model to describe the heterogeneity in internalizing problems and conduct problems trajectories in males and females respectively. Further, for ADHD, affected males were more likely to enter adolescence with already elevated symptoms whereas affected female trajectories were characterized by an escalation of symptoms during adolescence.ConclusionsThere are sex/gender differences in the levels and trajectories of specific mental health symptoms in early to middle adolescence; however, in both males and females there is a strong tendency for multiple issues to co-occur.

AB - BackgroundEarly to middle adolescence is a critical period of development for mental health issues. Illuminating sex/gender differences in mental health trajectories in this period is important for targeting screening and preventive interventions; however, evidence to date on the extent and nature of sex/gender differences in common mental health issue trajectories in this period has produced mixed findings. There is a particular gap in our knowledge of sex/gender differences in the joint trajectories of commonly co-occurring mental health issues in adolescence, given the strong tendency for mental health issues to co-occur.MethodWe applied sex/gender-stratified latent class growth analysis to an age-heterogeneous cohort (age 10–15) derived from the population-representative UK Household Longitudinal Study. We explored sex/gender differences in attention deficit hyperactivity disorder (ADHD) symptoms, internalizing problems, and conduct problems individually and jointly.ResultsWe found indications of sex/gender differences in a number of areas. There were fewer classes in the optimal model to describe the heterogeneity in internalizing problems and conduct problems trajectories in males and females respectively. Further, for ADHD, affected males were more likely to enter adolescence with already elevated symptoms whereas affected female trajectories were characterized by an escalation of symptoms during adolescence.ConclusionsThere are sex/gender differences in the levels and trajectories of specific mental health symptoms in early to middle adolescence; however, in both males and females there is a strong tendency for multiple issues to co-occur.

KW - ADHD

KW - adolescence

KW - conduct problems

KW - internalizing problems

KW - latent class growth analysis

KW - mental health

KW - trajectories

U2 - 10.1002/jcv2.12057

DO - 10.1002/jcv2.12057

M3 - Journal article

C2 - 37431498

VL - 2

SP - e12057

JO - JCPP Advances

JF - JCPP Advances

IS - 1

M1 - e12057

ER -