Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review
Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Conference contribution/Paper › peer-review
}
TY - GEN
T1 - Simulation guided design of a cryogenic probe for micrometer-scale in vivo MR imaging
AU - Hu, B.
AU - Glover, P.
AU - Benson, T.
PY - 2011
Y1 - 2011
N2 - The electromagnetic (EM) simulation guided design and operation of a receive-only liquid nitrogen (LN2) cooled coil suitable for medical imaging on a 3-T whole body MR scanner is presented. This process is easier and more cost-effective than building a range of coils. The performance of the designed probe was evaluated by comparison of signal-to-noise ratio (SNR) with the same radio-frequency (RF) coil operating at room temperature (RT). The cryogenic coil achieved a twofold SNR gain for small animal medical imaging applications. For mouse brain imaging, a 100 μm resolution was achieved in an imaging time of 3.5 minutes with an SNR of 25-40, revealing fine anatomical details unseen at lower resolution in the same time. The observed SNR was in good agreement with the expected SNR gain correlated to the loaded quality (Q) factor of RF coils from EM simulations.
AB - The electromagnetic (EM) simulation guided design and operation of a receive-only liquid nitrogen (LN2) cooled coil suitable for medical imaging on a 3-T whole body MR scanner is presented. This process is easier and more cost-effective than building a range of coils. The performance of the designed probe was evaluated by comparison of signal-to-noise ratio (SNR) with the same radio-frequency (RF) coil operating at room temperature (RT). The cryogenic coil achieved a twofold SNR gain for small animal medical imaging applications. For mouse brain imaging, a 100 μm resolution was achieved in an imaging time of 3.5 minutes with an SNR of 25-40, revealing fine anatomical details unseen at lower resolution in the same time. The observed SNR was in good agreement with the expected SNR gain correlated to the loaded quality (Q) factor of RF coils from EM simulations.
KW - Electromagnetic Modelling
KW - FDTD Method
KW - Magnetic Resonance Imaging
KW - Signal-To-Noise Ratio
U2 - 10.1109/ICCPS.2011.6092259
DO - 10.1109/ICCPS.2011.6092259
M3 - Conference contribution/Paper
SN - 978-1-4577-0602-8
SP - 647
EP - 651
BT - Computational Problem-Solving (ICCP), 2011 International Conference on
PB - IEEE
T2 - Computational Problem-Solving (ICCP), 2011 International Conference on
Y2 - 21 October 2011 through 23 October 2011
ER -