Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - "Supercritical carbon dioxide in water" emulsion-templated synthesis of porous calcium alginate hydrogels
AU - Partap, S.
AU - Rehman, I.
AU - Jones, J.R.
AU - Darr, J.A.
PY - 2006
Y1 - 2006
N2 - Supercritical carbon dioxide in water emulsion-templated synthesis of porous alginate hydrogels with a narrow range of macropore sizes was investigated. Hydrogels are three-dimensional (3D) polymeric networks capable of absorbing large quantities of water and are widely used in the biomedical fields as drug-delivery devices, wound dressings and scaffolds for tissue-engineering. The CO2 was used as a reagent increasing the acidity of aqueous phase and a templating agent. Results show that the reactive emulsion templating (RET) hydrogels were reversible under certain conditions, when left exposed to the atmosphere the CO2 escapes from the hydrogels and the alginate structure destabilizes within 48 hours.
AB - Supercritical carbon dioxide in water emulsion-templated synthesis of porous alginate hydrogels with a narrow range of macropore sizes was investigated. Hydrogels are three-dimensional (3D) polymeric networks capable of absorbing large quantities of water and are widely used in the biomedical fields as drug-delivery devices, wound dressings and scaffolds for tissue-engineering. The CO2 was used as a reagent increasing the acidity of aqueous phase and a templating agent. Results show that the reactive emulsion templating (RET) hydrogels were reversible under certain conditions, when left exposed to the atmosphere the CO2 escapes from the hydrogels and the alginate structure destabilizes within 48 hours.
KW - Absorption
KW - Acidity
KW - Carbon dioxide
KW - Drug dosage
KW - Emulsions
KW - Supercritical fluids
KW - Synthesis (chemical)
KW - Macropore sizes
KW - Polymeric networks
KW - Tissue engineering
KW - Water emulsion-templated synthesis
KW - Hydrogels
U2 - 10.1002/adma.200501423
DO - 10.1002/adma.200501423
M3 - Journal article
VL - 18
SP - 501
EP - 504
JO - Advanced Materials
JF - Advanced Materials
SN - 0935-9648
IS - 4
ER -