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Synthesis and in-vitro cytotoxicity analysis of microwave irradiated nano-apatites

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Synthesis and in-vitro cytotoxicity analysis of microwave irradiated nano-apatites. / Nazir, R.; Samad Khan, A.; Ahmed, A.; Ur-Rehman, A.; Anwar Chaudhry, A.; Ur Rehman, I.; Wong, F.S.L.

In: Ceramics International, Vol. 39, No. 4, 2013, p. 4339-4347.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Harvard

Nazir, R, Samad Khan, A, Ahmed, A, Ur-Rehman, A, Anwar Chaudhry, A, Ur Rehman, I & Wong, FSL 2013, 'Synthesis and in-vitro cytotoxicity analysis of microwave irradiated nano-apatites', Ceramics International, vol. 39, no. 4, pp. 4339-4347. https://doi.org/10.1016/j.ceramint.2012.11.017

APA

Nazir, R., Samad Khan, A., Ahmed, A., Ur-Rehman, A., Anwar Chaudhry, A., Ur Rehman, I., & Wong, F. S. L. (2013). Synthesis and in-vitro cytotoxicity analysis of microwave irradiated nano-apatites. Ceramics International, 39(4), 4339-4347. https://doi.org/10.1016/j.ceramint.2012.11.017

Vancouver

Nazir R, Samad Khan A, Ahmed A, Ur-Rehman A, Anwar Chaudhry A, Ur Rehman I et al. Synthesis and in-vitro cytotoxicity analysis of microwave irradiated nano-apatites. Ceramics International. 2013;39(4):4339-4347. https://doi.org/10.1016/j.ceramint.2012.11.017

Author

Nazir, R. ; Samad Khan, A. ; Ahmed, A. ; Ur-Rehman, A. ; Anwar Chaudhry, A. ; Ur Rehman, I. ; Wong, F.S.L. / Synthesis and in-vitro cytotoxicity analysis of microwave irradiated nano-apatites. In: Ceramics International. 2013 ; Vol. 39, No. 4. pp. 4339-4347.

Bibtex

@article{b314b7d0c6e9470d8c4f428448433df9,
title = "Synthesis and in-vitro cytotoxicity analysis of microwave irradiated nano-apatites",
abstract = "Nano-sized calcium deficient apatite (CDA) micelles were synthesized through microwave assisted the wet precipitation technique. Cetyltrimethylammonium bromide (CTAB) was employed as surface template to furnish the CDA particles with tailored size and shape. As-precipitated CDA was heat treated to observe the effect of heat treatment temperature on the interatomic rearrangement of entities within the apatite lattice. This transformation is responsible for conversion of CDA to β-tricalcium phosphate (β-TCP) at specific temperature. The phase purity, particles size, morphology and transformation kinetics were analyzed using X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM) and Thermogravimetric Analysis (TGA). In-vitro studies were performed on β-TCP with three cell lines: osteoblasts, HeLa, and SF 767. The results showed that nano-sized particles were successfully synthesized in short time. The cells had appreciable proliferation/attachment on the surface of these nano-particles. It is concluded that the microwave irradiated synthesized β-TCP has good capacity in terms of biocompatibility and has the potential to be used in hard tissue regeneration applications. {\textcopyright} 2012 Elsevier Ltd and Techna Group S.r.l.",
keywords = "Cytotoxicity, Microwave assisted synthesis, Nano-particles, Tricalcium phosphate (TCP), Calcium deficient apatites, Cell lines, Cetyltrimethylammonium bromide, Effect of heat treatments, In-vitro, Microwave assisted, Nano-apatites, Nano-sized particles, Particles sizes, Phase purity, Size and shape, Surface templates, Transformation kinetics, Tricalcium phosphates, Wet precipitation, Apatite, Biocompatibility, Cell culture, Fourier transform infrared spectroscopy, Microwaves, Nanoparticles, Particle size, Scanning electron microscopy, Thermogravimetric analysis, X ray diffraction, Synthesis (chemical)",
author = "R. Nazir and {Samad Khan}, A. and A. Ahmed and A. Ur-Rehman and {Anwar Chaudhry}, A. and {Ur Rehman}, I. and F.S.L. Wong",
year = "2013",
doi = "10.1016/j.ceramint.2012.11.017",
language = "English",
volume = "39",
pages = "4339--4347",
journal = "Ceramics International",
issn = "0272-8842",
publisher = "Elsevier Ltd",
number = "4",

}

RIS

TY - JOUR

T1 - Synthesis and in-vitro cytotoxicity analysis of microwave irradiated nano-apatites

AU - Nazir, R.

AU - Samad Khan, A.

AU - Ahmed, A.

AU - Ur-Rehman, A.

AU - Anwar Chaudhry, A.

AU - Ur Rehman, I.

AU - Wong, F.S.L.

PY - 2013

Y1 - 2013

N2 - Nano-sized calcium deficient apatite (CDA) micelles were synthesized through microwave assisted the wet precipitation technique. Cetyltrimethylammonium bromide (CTAB) was employed as surface template to furnish the CDA particles with tailored size and shape. As-precipitated CDA was heat treated to observe the effect of heat treatment temperature on the interatomic rearrangement of entities within the apatite lattice. This transformation is responsible for conversion of CDA to β-tricalcium phosphate (β-TCP) at specific temperature. The phase purity, particles size, morphology and transformation kinetics were analyzed using X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM) and Thermogravimetric Analysis (TGA). In-vitro studies were performed on β-TCP with three cell lines: osteoblasts, HeLa, and SF 767. The results showed that nano-sized particles were successfully synthesized in short time. The cells had appreciable proliferation/attachment on the surface of these nano-particles. It is concluded that the microwave irradiated synthesized β-TCP has good capacity in terms of biocompatibility and has the potential to be used in hard tissue regeneration applications. © 2012 Elsevier Ltd and Techna Group S.r.l.

AB - Nano-sized calcium deficient apatite (CDA) micelles were synthesized through microwave assisted the wet precipitation technique. Cetyltrimethylammonium bromide (CTAB) was employed as surface template to furnish the CDA particles with tailored size and shape. As-precipitated CDA was heat treated to observe the effect of heat treatment temperature on the interatomic rearrangement of entities within the apatite lattice. This transformation is responsible for conversion of CDA to β-tricalcium phosphate (β-TCP) at specific temperature. The phase purity, particles size, morphology and transformation kinetics were analyzed using X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM) and Thermogravimetric Analysis (TGA). In-vitro studies were performed on β-TCP with three cell lines: osteoblasts, HeLa, and SF 767. The results showed that nano-sized particles were successfully synthesized in short time. The cells had appreciable proliferation/attachment on the surface of these nano-particles. It is concluded that the microwave irradiated synthesized β-TCP has good capacity in terms of biocompatibility and has the potential to be used in hard tissue regeneration applications. © 2012 Elsevier Ltd and Techna Group S.r.l.

KW - Cytotoxicity

KW - Microwave assisted synthesis

KW - Nano-particles

KW - Tricalcium phosphate (TCP)

KW - Calcium deficient apatites

KW - Cell lines

KW - Cetyltrimethylammonium bromide

KW - Effect of heat treatments

KW - In-vitro

KW - Microwave assisted

KW - Nano-apatites

KW - Nano-sized particles

KW - Particles sizes

KW - Phase purity

KW - Size and shape

KW - Surface templates

KW - Transformation kinetics

KW - Tricalcium phosphates

KW - Wet precipitation

KW - Apatite

KW - Biocompatibility

KW - Cell culture

KW - Fourier transform infrared spectroscopy

KW - Microwaves

KW - Nanoparticles

KW - Particle size

KW - Scanning electron microscopy

KW - Thermogravimetric analysis

KW - X ray diffraction

KW - Synthesis (chemical)

U2 - 10.1016/j.ceramint.2012.11.017

DO - 10.1016/j.ceramint.2012.11.017

M3 - Journal article

VL - 39

SP - 4339

EP - 4347

JO - Ceramics International

JF - Ceramics International

SN - 0272-8842

IS - 4

ER -