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Synthesis of cleviolide and the scobinolides

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<mark>Journal publication date</mark>1/07/1993
<mark>Journal</mark>SYNLETT
Issue number7
Volume1993
Number of pages3
Pages (from-to)463-465
Publication StatusPublished
<mark>Original language</mark>English

Abstract

The polyunsaturated 2(5H)-furanone natural products cleviolide (1) and (E)- A nd (Z)-scobinolide (2) and (3) have been efficiently synthesized in convergent fashion via palladiumcatalyzed coupling of 4-tributylstannyl-2(5H)-furanone (4) and 1-iodo-4-methylpent-3-en-1-yne (5).