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Temperature dependent FTIR spectroscopic study of the interaction of alpha-tocopherol and alpha-tocopheryl acetate with phospholipid bilayers.

Research output: Contribution to journalJournal articlepeer-review

  • S. Akyüz
  • J. Eric D. Davies
<mark>Journal publication date</mark>11/08/1997
<mark>Journal</mark>Journal of Molecular Structure
Issue number1-2
Number of pages6
Pages (from-to)65-70
Publication StatusPublished
<mark>Original language</mark>English


FTIR spectroscopy has been employed in order to investigate α-tocopherol (α-T) and α-tocopheryl acetate (α-TA) induced effects on the molecular organization of dimyristoyl- L -α-phosphatidylcholine (DMPC) bilayers, at various temperatures and concentrations. It was concluded that α-T interacts much more strongly than α-TA, indicating that α-T has a more polar location in the membrane than α-TA. The observed changes in the carbonyl and phosphate group vibrational modes of DMPC on addition of α-T or α-TA are discussed