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Tetranuclear Zn2Ln2 coordination clusters as catalysts in the Petasis borono-Mannich multicomponent reaction

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<mark>Journal publication date</mark>15/08/2016
<mark>Journal</mark>RSC Advances
Issue number82
Volume6
Number of pages5
Pages (from-to)79180-79184
Publication StatusPublished
<mark>Original language</mark>English

Abstract

We report herein for the first time the efficiency of heteronuclear Zn/Ln coordination clusters (CCs) as catalysts for the multicomponent Mannich-type condensation that involves amines, aldehydes and boronic acids, known as the Petasis borono-Mannich (RBR) reaction. The reaction proceeds in very good to excellent yields (84-98%, 17 products) at room temperature with catalyst loadings as low as 1.0 mol%.