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The developmental basis of fingerprint pattern formation and variation.

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The developmental basis of fingerprint pattern formation and variation. / Glover, James D.; Sudderick, ZR; Shih, BB et al.
In: Cell, 09.02.2023, p. 940-956.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Glover, JD, Sudderick, ZR, Shih, BB, Batho-Samblas, C, Charlton, L, Krause, AL, Anderson, C, Riddell, J, Balic, A, Li, J, Klika, V, Woolley, TE, Gaffney, EA, Corsinotti, A, Anderson, RA, Johnston, LJ, Brown, SJ, Wang, S, Chen, Y, Crichton, M & Headon, DJ 2023, 'The developmental basis of fingerprint pattern formation and variation.', Cell, pp. 940-956. https://doi.org/10.1016/j.cell.2023.01.015

APA

Glover, J. D., Sudderick, ZR., Shih, BB., Batho-Samblas, C., Charlton, L., Krause, AL., Anderson, C., Riddell, J., Balic, A., Li, J., Klika, V., Woolley, TE., Gaffney, EA., Corsinotti, A., Anderson, RA., Johnston, LJ., Brown, SJ., Wang, S., Chen, Y., ... Headon, DJ. (2023). The developmental basis of fingerprint pattern formation and variation. Cell, 940-956. https://doi.org/10.1016/j.cell.2023.01.015

Vancouver

Glover JD, Sudderick ZR, Shih BB, Batho-Samblas C, Charlton L, Krause AL et al. The developmental basis of fingerprint pattern formation and variation. Cell. 2023 Feb 9;940-956. doi: 10.1016/j.cell.2023.01.015

Author

Glover, James D. ; Sudderick, ZR ; Shih, BB et al. / The developmental basis of fingerprint pattern formation and variation. In: Cell. 2023 ; pp. 940-956.

Bibtex

@article{00da37a3be0947788890039b7836b1c3,
title = "The developmental basis of fingerprint pattern formation and variation.",
abstract = "Fingerprints are complex and individually unique patterns in the skin. Established prenatally, the molecular and cellular mechanisms that guide fingerprint ridge formation and their intricate arrangements are unknown. Here we show that fingerprint ridges are epithelial structures that undergo a truncated hair follicle developmental program and fail to recruit a mesenchymal condensate. Their spatial pattern is established by a Turing reaction-diffusion system, based on signaling between EDAR, WNT, and antagonistic BMP pathways. These signals resolve epithelial growth into bands of focalized proliferation under a precociously differentiated suprabasal layer. Ridge formation occurs as a set of waves spreading from variable initiation sites defined by the local signaling environments and anatomical intricacies of the digit, with the propagation and meeting of these waves determining the type of pattern that forms. Relying on a dynamic patterning system triggered at spatially distinct sites generates the characteristic types and unending variation of human fingerprint patterns.",
author = "Glover, {James D.} and ZR Sudderick and BB Shih and C Batho-Samblas and L Charlton and AL Krause and C Anderson and J Riddell and A Balic and J Li and V Klika and TE Woolley and EA Gaffney and A Corsinotti and RA Anderson and LJ Johnston and SJ Brown and S Wang and Y Chen and Michael Crichton and DJ Headon",
year = "2023",
month = feb,
day = "9",
doi = "10.1016/j.cell.2023.01.015",
language = "Undefined/Unknown",
pages = "940--956",
journal = "Cell",
issn = "0092-8674",
publisher = "Cell Press",

}

RIS

TY - JOUR

T1 - The developmental basis of fingerprint pattern formation and variation.

AU - Glover, James D.

AU - Sudderick, ZR

AU - Shih, BB

AU - Batho-Samblas, C

AU - Charlton, L

AU - Krause, AL

AU - Anderson, C

AU - Riddell, J

AU - Balic, A

AU - Li, J

AU - Klika, V

AU - Woolley, TE

AU - Gaffney, EA

AU - Corsinotti, A

AU - Anderson, RA

AU - Johnston, LJ

AU - Brown, SJ

AU - Wang, S

AU - Chen, Y

AU - Crichton, Michael

AU - Headon, DJ

PY - 2023/2/9

Y1 - 2023/2/9

N2 - Fingerprints are complex and individually unique patterns in the skin. Established prenatally, the molecular and cellular mechanisms that guide fingerprint ridge formation and their intricate arrangements are unknown. Here we show that fingerprint ridges are epithelial structures that undergo a truncated hair follicle developmental program and fail to recruit a mesenchymal condensate. Their spatial pattern is established by a Turing reaction-diffusion system, based on signaling between EDAR, WNT, and antagonistic BMP pathways. These signals resolve epithelial growth into bands of focalized proliferation under a precociously differentiated suprabasal layer. Ridge formation occurs as a set of waves spreading from variable initiation sites defined by the local signaling environments and anatomical intricacies of the digit, with the propagation and meeting of these waves determining the type of pattern that forms. Relying on a dynamic patterning system triggered at spatially distinct sites generates the characteristic types and unending variation of human fingerprint patterns.

AB - Fingerprints are complex and individually unique patterns in the skin. Established prenatally, the molecular and cellular mechanisms that guide fingerprint ridge formation and their intricate arrangements are unknown. Here we show that fingerprint ridges are epithelial structures that undergo a truncated hair follicle developmental program and fail to recruit a mesenchymal condensate. Their spatial pattern is established by a Turing reaction-diffusion system, based on signaling between EDAR, WNT, and antagonistic BMP pathways. These signals resolve epithelial growth into bands of focalized proliferation under a precociously differentiated suprabasal layer. Ridge formation occurs as a set of waves spreading from variable initiation sites defined by the local signaling environments and anatomical intricacies of the digit, with the propagation and meeting of these waves determining the type of pattern that forms. Relying on a dynamic patterning system triggered at spatially distinct sites generates the characteristic types and unending variation of human fingerprint patterns.

UR - https://doi.org/10.1016/j.cell.2023.01.015

U2 - 10.1016/j.cell.2023.01.015

DO - 10.1016/j.cell.2023.01.015

M3 - Journal article

C2 - 36764291

SP - 940

EP - 956

JO - Cell

JF - Cell

SN - 0092-8674

ER -